Dr. Alan Lesse
Medicine
Associate Professor of Pharmacology and Toxicology and Medicine
VA Western New York Healthcare System
Research (151)
3495 Bailey Avenue
Buffalo NY, 14215
Phone: (716) 862-6532
Fax: (716) 862-6526
Email: camlesse@buffalo.edu
URL: http://www.smbs.buffalo.edu/med/ID/images/facultypic/lesse.jpg

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OFFICE LOCATIONS

VA Western New York Healthcare System
3495 Bailey Ave
Buffalo NY, 14215

Phone: 716-862-7874
Fax: 716-862-6536
Contact: Cookie Thurston
Email: camlesse@buffalo.edu
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Insurance Accepted
Veterans Administration


SPECIALTIES

Infectious Disease


EDUCATION

1981 MD, University of Virginia
1977 BA, University of Virginia


PUBLICATIONS

Ruckdeschel EA, Kirkham C, Lesse AJ, Hu Z, Murphy TF; Mining the Moraxella catarrhalis genome: identification of potential vaccine antigens expressed during human infection.; Infect Immun; 2008 Apr; 76(4); 1599-1607
Murphy TF, Brauer AL, Sethi S, Kilian M, Cai X, Lesse AJ; Haemophilus haemolyticus: a human respiratory tract commensal to be distinguished from Haemophilus influenzae.; J Infect Dis; 2007 Jan; 195(1); 81-89
Lesse AJ, Mylotte JM; Clinical and molecular epidemiology of nursing home-associated Staphylococcus aureus bacteremia.; Am J Infect Control; 2006 Dec; 34(10); 642-650
Fernaays MM, Lesse AJ, Cai X, Murphy TF; Characterization of igaB, a second immunoglobulin A1 protease gene in nontypeable Haemophilus influenzae.; Infect Immun; 2006 Oct; 74(10); 5860-5870
Murphy TF, Kirkham C, Lesse AJ; Construction of a mutant and characterization of the role of the vaccine antigen P6 in outer membrane integrity of nontypeable Haemophilus influenzae.; Infect Immun; 2006 Sep; 74(9); 5169-5176
Fernaays MM, Lesse AJ, Sethi S, Cai X, Murphy TF; Differential genome contents of nontypeable Haemophilus influenzae strains from adults with chronic obstructive pulmonary disease.; Infect Immun; 2006 Jun; 74(6); 3366-3374
Murphy TF, Kirkham C, Sethi S, Lesse AJ; Expression of a peroxiredoxin-glutaredoxin by Haemophilus influenzae in biofilms and during human respiratory tract infection.; FEMS Immunol Med Microbiol; 2005 Apr; 44(1); 81-89
Adlowitz DG, Hiltke T, Lesse AJ, Murphy TF; Identification and characterization of outer membrane proteins G1a and G1b of Moraxella catarrhalis.; Vaccine; 2004 Jun; 22(20); 2533-2540
Johnson JR, Gajewski A, Lesse AJ, Russo TA; Extraintestinal pathogenic Escherichia coli as a cause of invasive nonurinary infections.; J Clin Microbiol; 2003 Dec; 41(12); 5798-5802
Segada LM, Carlone GM, Gheesling LL, Lesse AJ; Characterization of P1-deficient isogenic mutant of Haemophilus influenzae biogroup aegyptius associated with Brazilian purpuric fever.; Microb Pathog; 2000 Mar; 28(3); 145-155
Russo TA, Wenderoth S, Carlino UB, Merrick JM, Lesse AJ; Identification, genomic organization, and analysis of the group III capsular polysaccharide genes kpsD, kpsM, kpsT, and kpsE from an extraintestinal isolate of Escherichia coli (CP9, O4/K54/H5).; J Bacteriol; 1998 Jan; 180(2); 338-349
Segada LM, Lesse AJ; Creation of an isogenic P1-deficient mutant of Haemophilus influenzae biogroup aegyptius.; Gene; 1997 Dec; 204(1-2); 185-194
Inzana TJ, Hensley J, McQuiston J, Alan Lesse, Anthony Campagnari, Boyle SM, Apicella MA; Phase variation and conservation of lipooligosaccharide epitopes in Haemophilus somnus.; Infect Immun; 1997 Nov; 65(11); 4675-4681
Reed RB, Frost JB, Kort K, Myers SD, Lesse AJ; DNA sequence analysis and restriction fragment length polymorphisms of the P1 gene of Haemophilus influenzae biogroup aegyptius associated with Brazilian purpuric fever.; Infect Immun; 1996 Sep; 64(9); 3666-3672
Antalek MD, Joseph Mylotte, Alan Lesse, John Sellick; Clinical and molecular epidemiology of Enterococcus faecalis bacteremia, with special reference to strains with high-level resistance to gentamicin.; Clin Infect Dis; 1995 Jan; 20(1); 103-109
Anthony Campagnari, Karalus R, Apicella M, Melaugh W, Alan Lesse, Gibson BW; Use of pyocin to select a Haemophilus ducreyi variant defective in lipooligosaccharide biosynthesis.; Infect Immun; 1994 Jun; 62(6); 2379-2386
Lesse AJ, Bittner WE; Expression of an immunoreactive 72 kDa protein in strains of Haemophilus influenzae biogroup aegyptius associated with Brazilian purpuric fever.; Microb Pathog; 1993 Oct; 15(4); 319-326
Murphy TF, Kirkham C, Lesse AJ; The major heat-modifiable outer membrane protein CD is highly conserved among strains of Branhamella catarrhalis.; Mol Microbiol; 1993 Oct; 10(1); 87-97
Tunkel AR, Wispelwey B, Quagliarello VJ, Rosser SW, Lesse AJ, Hansen EJ, Scheld WM; Pathophysiology of blood-brain barrier alterations during experimental Haemophilus influenzae meningitis.; J Infect Dis; 1992 Jun; 165 S; 119-120
Lesse AJ, Gheesling LL, Bittner WE, Myers SD, Carlone GM; Stable, conserved outer membrane epitope of strains of Haemophilus influenzae biogroup aegyptius associated with Brazilian purpuric fever.; Infect Immun; 1992 Apr; 60(4); 1351-1357
Spinola SM, Kwaik YA, Alan Lesse, Anthony Campagnari, Apicella MA; Cloning and expression in Escherichia coli of a Haemophilus influenzae type b lipooligosaccharide synthesis gene(s) that encodes a 2-keto-3-deoxyoctulosonic acid epitope.; Infect Immun; 1990 Jun; 58(6); 1558-1564
Mandrell RE, Lesse AJ, Sugai JV, Shero M, Griffiss JM, Cole JA, Parsons NJ, Smith H, Morse SA, Apicella MA; In vitro and in vivo modification of Neisseria gonorrhoeae lipooligosaccharide epitope structure by sialylation.; J Exp Med; 1990 May; 171(5); 1649-1664
Anthony Campagnari, Spinola SM, Alan Lesse, Kwaik YA, Mandrell RE, Apicella MA; Lipooligosaccharide epitopes shared among gram-negative non-enteric mucosal pathogens.; Microb Pathog; 1990 May; 8(5); 353-362
Alan Lesse, Anthony Campagnari, Bittner WE, Apicella MA; Increased resolution of lipopolysaccharides and lipooligosaccharides utilizing tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis.; J Immunol Methods; 1990 Jan; 126(1); 109-117
Wispelwey B, Lesse AJ, Hansen EJ, Scheld WM; Haemophilus influenzae lipopolysaccharide-induced blood brain barrier permeability during experimental meningitis in the rat.; J Clin Invest; 1988 Oct; 82(4); 1339-1346
Lesse AJ, Moxon ER, Zwahlen A, Scheld WM; Role of cerebrospinal fluid pleocytosis and Haemophilus influenzae type b capsule on blood brain barrier permeability during experimental meningitis in the rat.; J Clin Invest; 1988 Jul; 82(1); 102-109
Lesse AJ, Freer C, Salata RA, Francis JB, Scheld WM; Oral ciprofloxacin therapy for gram-negative bacillary osteomyelitis.; Am J Med; 1987 Apr; 82(4A); 247-253



 
Dr. Alan Lesse
Dr. Alan Lesse