| Paradkar PN, Roth JA; Expression of the 1B isoforms of divalent metal transporter (DMT1) is regulated by interaction of NF-Y with a CCAAT-box element near the transcription start site.; J Cell Physiol; 2007 Apr; 211(1); 183-188 |
| Garrick MD, Kuo HC, Vargas F, Singleton S, Zhao L, Smith JJ, Paradkar P, Roth JA, Garrick LM; Comparison of mammalian cell lines expressing distinct isoforms of divalent metal transporter 1 in a tetracycline-regulated fashion.; Biochem J; 2006 Sep; 398(3); 539-546 |
| Paradkar PN, Roth JA; Nitric oxide transcriptionally down-regulates specific isoforms of divalent metal transporter (DMT1) via NF-kappaB.; J Neurochem; 2006 Mar; 96(6); 1768-1777 |
| Garrick MD, Singleton ST, Vargas F, Kuo HC, Zhao L, Knöpfel M, Davidson T, Costa M, Paradkar P, Roth JA, Garrick LM; DMT1: which metals does it transport?; Biol Res; 2006 Jan; 39(1); 79-85 |
| Roth JA; Homeostatic and toxic mechanisms regulating manganese uptake, retention, and elimination.; Biol Res; 2006; 39; 45-57 |
| Paradkar, P, Roth JA; Post-translational and Transcriptional Regulation of DMT1 during P19 Embryonic Carcinoma Cell Differentiation by Retinoic Acid; biochemical journal; 2006; 394; 173-183 |
| Lis A, Paradkar PN, Singleton S, Kuo HC, Garrick MD, Roth JA; Hypoxia induces changes in expression of isoforms of the divalent metal transporter (DMT1) in rat pheochromocytoma (PC12) cells.; Biochem Pharmacol; 2005 Jun; 69(11); 1647-1655 |
| Kuo HC, Smith JJ, Lis A, Zhao L, Gonsiorek EA, Zhou X, Higgins DM, Roth JA, Garrick MD, Garrick LM; Computer-identified nuclear localization signal in exon 1A of the transporter DMT1 is essentially ineffective in nuclear targeting.; J Neurosci Res; 2004 May; 76(4); 497-511 |
| Lis A, Barone TA, Paradkar PN, Plunkett RJ, Roth JA; Expression and localization of different forms of DMT1 in normal and tumor astroglial cells.; Brain Res Mol Brain Res; 2004 Mar; 122(1); 62-70 |
| Kuo, H.-C., Smith, J.J., Lis, A., Zhou, H., Gonsiorek, E.A., Zhou, X., Higgins, D.M., Roth, J.A., Garrick, M.D. and Garrick, L.M; A Computer-Identified Nuclear Localization Signal in Exon 1A of the Transporter DMT1 is Essentially Ineffective in Nuclear Targeting; J. Neurosci. Res.; 2004; 75; |
| ROTH JA; Expression and Localization of Different Forms of DMT1 in Normal and Tumor Astroglial Cells; Mol. Brain Research; 2004; 122; 62-70 |
| Roth JA, Garrick MD; Iron interactions and other biological reactions mediating the physiological and toxic actions of manganese.; Biochem Pharmacol; 2003 Jul; 66(1); 1-13 |
| Garrick MD, Dolan KG, Horbinski C, Ghio AJ, Higgins D, Porubcin M, Moore EG, Hainsworth LN, Umbreit JN, Conrad ME, Feng L, Lis A, Roth JA, Singleton S, Garrick LM; DMT1: a mammalian transporter for multiple metals.; Biometals; 2003 Mar; 16(1); 41-54 |
| Michael Garrick, Dolan, KG, Horbinski, C, Ghio, A, Dennis Higgins, Porubcin, M, Moore, EG, Hainsworth, LN, Umbreit, JN, Conrad, ME, Feng, L, Lis, A, Jerome Roth; DMT1: A Mammalian Transporter for Multiple Metals. BioMetals; Biometals; 2003; 16; 41-54 |
| Jerome Roth, Craig Horbinski, Dennis Higgins, Pam Lein, Michael Garrick; Mechanisms of manganese-induced rat pheochromocytoma (PC12) cell death and cell differentiation
; Neurotoxicology; 2002 Jul; 23(7); 147-157 |
| Roth JA, Feng L, Dolan KG, Lis A, Garrick MD; Effect of the iron chelator desferrioxamine on manganese-induced toxicity of rat pheochromocytoma (PC12) cells.; J Neurosci Res; 2002 Apr; 68(1); 76-83 |
| Jerome Roth
Craig Horbinski
Dennis Higgins
Pam Lein
Michael Garrick
; Manganese-induced rat pheochromocytoma (PC12) cell death and cell differentiation; Neurotoxicology; 2002 Jan; 23; 147-157 |
| Roth JA, Horbinski C, Higgins D, Lein P, Garrick MD; Mechanisms of manganese-induced rat pheochromocytoma (PC12) cell death and cell differentiation.; Neurotoxicology; 2002; 23; 147-157 |
| Roth JA, Rosenblatt T, Lis A, Bucelli R; Melatonin-induced suppression of PC12 cell growth is mediated by its Gi coupled transmembrane receptors.; Brain Res; 2001 Nov; 919(1); 139-146 |
| Lein P, Gallagher PJ, Amodeo J, Howie H, Roth JA; Manganese induces neurite outgrowth in PC12 cells via upregulation of alpha(v) integrins.; Brain Res; 2000 Dec; 885(2); 220-230 |
| Roth JA, Feng L, Walowitz J, Browne RW; Manganese-induced rat pheochromocytoma (PC12) cell death is independent of caspase activation.; J Neurosci Res; 2000 Jul; 61(2); 162-171 |
| Jerome Roth, Horbinski C, Feng L, Dolan KG, Dennis Higgins, Michael Garrick; Differential localization of divalent metal transporter 1 with and without iron response element in rat PC12 and sympathetic neuronal cells.; J Neurosci; 2000; 20; 7595-7601 |
| Walowitz JL, Roth JA; Activation of ERK1 and ERK2 is required for manganese-induced neurite outgrowth in rat pheochromocytoma (PC12) cells.; J Neurosci Res; 1999 Sep; 57(6); 847-854 |
| Roth JA, Kim BG, Lin WL, Cho MI; Melatonin promotes osteoblast differentiation and bone formation; J Biol Chem; 1999 Jul; 274(31); 22041-22047 |
| Larsen KE, Pacheco M, Roth J, Aletta JM; Increased MAP1B expression without increased phosphorylation in manganese-treated PC12Mn cells.; Exp Cell Res; 1998 Nov; 245(1); 105-115 |
| Roth J, Rabin R, Agnello, K; Melatonin suppression of PC12 cell growth and death; Brain Research; 1997; 768; 63-70 |
| Lin WH, Marcucci K, Roth JA; Effect of manganese on tyrosylprotein sulfotransferase activity in PC12 cells.; Biochem Pharmacol; 1994 Apr; 47(9); 1575-1580 |
| Lin WH, Higgins D, Pacheco M, Aletta J, Perini S, Marcucci KA, Roth JA; Manganese induces spreading and process outgrowth in rat pheochromocytoma (PC12) cells.; J Neurosci Res; 1993; 34; 546-561 |
| Spaulding SW, Smith TJ, Hinkle PM, Davis FB, Kung MP, Roth JA; Studies on the biological activity of triiodothyronine sulfate.; J Clin Endocrinol Metab; 1992 May; 74(5); 1062-1067 |
| Lin WH, Marcucci KA, Rabin RA, Roth JA; 2-Chloroadenosine decreases tyrosylprotein sulfotransferase activity in the Golgi apparatus in PC12 cells. Evidence for a novel receptor.; J Biol Chem; 1991 Aug; 266(22); 14457-14463 |
| Roth JA, Marcucci K, Lin WH, Napoli JL, Wagner JA, Rabin R; Increase in beta-1,4-galactosyltransferase activity during PC12 cell differentiation induced by forskolin and 2-chloroadenosine.; J Neurochem; 1991 Aug; 57(2); 708-713 |
| Zou JY, Petney R, Roth JA; Immunohistochemical detection of phenol sulfotransferase-containing neurons in human brain.; J Neurochem; 1990 Oct; 55(4); 1154-1158 |
| Roth JA, Grossman MH, Adolf M; Variation in hepatic membrane-bound catechol-O-methyltransferase activity in Fischer and Wistar-Furth strains of rat.; Biochem Pharmacol; 1990 Sep; 40(5); 1151-1153 |
| Lin WH, Roth JA; Characterization of a tyrosylprotein sulfotransferase in human liver.; Biochem Pharmacol; 1990 Aug; 40(3); 629-635 |
| Falany CN, Vazquez ME, Heroux JA, Roth JA; Purification and characterization of human liver phenol-sulfating phenol sulfotransferase.; Arch Biochem Biophys; 1990 May; 278(2); 312-318 |
| Rens-Domiano S, Hortin GL, Roth JA; Sulfation of tert-butoxycarbonylcholecystokinin and other peptides by rat liver tyrosylprotein sulfotransferase.; Mol Pharmacol; 1989 Oct; 36(4); 647-653 |
| Rens-Domiano S, Roth JA; Characterization and post-natal development of rat cerebellum tyrosylprotein sulfotransferase.; Biochem Pharmacol; 1989 Sep; 38(17); 2930-2932 |
| Heroux JA, Falany CN, Roth JA; Immunological characterization of human phenol sulfotransferase.; Mol Pharmacol; 1989 Jul; 36(1); 29-33 |
| Kung MP, Nickerson PA, Sansone FM, Olson JR, Kostyniak PJ, Adolf MA, Roth JA; Effect of chronic exposure to hexachlorophene on rat brain cell specific marker enzymes.; Neurotoxicology; 1989 Jun; 10(2); 201-210 |
| Kung MP, Kostyniak PJ, Olson JR, Sansone FM, Nickerson PA, Malone MA, Ziembiec N, Roth JA; Cell specific enzyme markers as indicators of neurotoxicity: effects of acute exposure to methylmercury.; Neurotoxicology; 1989 Jan; 10(1); 41-52 |
| Kung MP, Kostyniak PJ, Olson JR, Sansone FM, Nickerson PA, Malone MA, Ziembiec N, Roth JA; Cell specific enzyme markers as indicators of neurotoxicity: effects of acuteexposure to methylmercury.; Neurotoxicology; 1989; 10(1); 41-52 |
| Rens-Domiano S, Roth JA; Characterization of tyrosylprotein sulfotransferase from rat liver and other tissues.; J Biol Chem; 1989 Jan; 264(2); 899-905 |
| Kung MP, Nickerson PA, Sansone FM, Olson JR, Kostyniak PJ, Adolf MA, Lein PJ, Roth JA; Effect of short-term exposure to hexachlorophene on rat brain cell specific marker enzymes.; Fundam Appl Toxicol; 1988 Oct; 11(3); 519-527 |
| Heroux JA, Roth JA; Physical characterization of a monoamine-sulfating form of phenol sulfotransferase from human platelets.; Mol Pharmacol; 1988 Aug; 34(2); 194-199 |
| Kung MP, Spaulding SW, Roth JA; Desulfation of 3,5,3'-triiodothyronine sulfate by microsomes from human and rat tissues.; Endocrinology; 1988 Apr; 122(4); 1195-1200 |
| Kung MP, Roth JA; Cellular localization of soluble and membrane-bound forms of arylsulfatase in rat brain.; Brain Res; 1987 Sep; 419(1-2); 141-146 |
| Francis A, Whittemore R, Jeffery DR, Pearce LB, Roth JA; Catecholamine-metabolizing enzyme activity in the nigrostriatal system.; Biochem Pharmacol; 1987 Jul; 36(13); 2229-2231 |
| Rens-Domiano SS, Roth JA; Inhibition of M and P phenol sulfotransferase by analogues of 3'-phosphoadenosine-5'-phosphosulfate.; J Neurochem; 1987 May; 48(5); 1411-1415 |
| Jeffery DR, Roth JA; Kinetic reaction mechanism for magnesium binding to membrane-bound and soluble catechol O-methyltransferase.; Biochemistry; 1987 May; 26(10); 2955-2958 |
| Kung MP, Kostyniak P, Olson J, Malone M, Roth JA; Studies of the in vitro effect of methylmercury chloride on rat brain neurotransmitter enzymes.; J Appl Toxicol; 1987 Apr; 7(2); 119-121 |
| Roth JA, Morphy M, Szymanski H; Formation of adenosine-5'-phosphosulfate from 3'-phosphoadenosine-5'-phosphosulfate in human platelets.; Biochem Pharmacol; 1986 Oct; 35(20); 3646-3649 |
| Whittemore RM, Pearce LB, Roth JA; Purification and kinetic characterization of a phenol-sulfating form of phenol sulfotransferase from human brain.; Arch Biochem Biophys; 1986 Sep; 249(2); 464-471 |
| Whittemore RM, Roth JA; Effect of phosphatase inhibition of in vitro dopamine sulfation and 3'-phosphoadenosine-5'-phosphosulfate catabolism in human brain.; Biochem Pharmacol; 1985 Nov; 34(21); 3853-3856 |
| Whittemore RM, Roth JA; A modified Ecteola cellulose assay for M and P phenol sulfotransferase.; Biochem Pharmacol; 1985 May; 34(10); 1647-1652 |
| Francis A, Pearce LB, Roth JA; Cellular localization of MAO A and B in brain: evidence from kainic acid lesions in striatum.; Brain Res; 1985 May; 334(1); 59-64 |
| Whittemore RM, Pearce LB, Roth JA; Purification and kinetic characterization of a dopamine-sulfating form of phenol sulfotransferase from human brain.; Biochemistry; 1985 May; 24(10); 2477-2482 |
| Pearce LB, Roth JA; Human brain monoamine oxidase type B: mechanism of deamination as probed by steady-state methods.; Biochemistry; 1985 Apr; 24(8); 1821-1826 |
| Jeffery DR, Roth JA; Purification and kinetic mechanism of human brain soluble catechol-O-methyltransferase.; J Neurochem; 1985 Mar; 44(3); 881-885 |
| Pearce LB, Roth JA; Monoamine oxidase: separation of the type A and B activities.; Biochem Pharmacol; 1984 Jun; 33(11); 1809-1811 |
| Rivett AJ, Francis A, Whittemore R, Roth JA; Sulfate conjugation of dopamine in rat brain: regional distribution of activity and evidence for neuronal localization.; J Neurochem; 1984 May; 42(5); 1444-1449 |
| Jeffery DR, Roth JA; Characterization of membrane-bound and soluble catechol-O-methyltransferase from human frontal cortex.; J Neurochem; 1984 Mar; 42(3); 826-832 |
| Pearce LB, Roth JA; Human brain monoamine oxidase: solubilization and kinetics of inhibition by octylglucoside.; Arch Biochem Biophys; 1983 Jul; 224(2); 464-472 |
| Rivett AJ, Francis A, Roth JA; Localization of membrane-bound catechol-O-methyltransferase.; J Neurochem; 1983 May; 40(5); 1494-1496 |
| Francis A, Rivett AJ, Roth JA; Activity of neuron-specific enolase in normal and lesioned rat brain.; Brain Res; 1983 Mar; 263(1); 89-95 |
| Rivett AJ, Francis A, Roth JA; Distinct cellular localization of membrane-bound and soluble forms of catechol-O-methyltransferase in brain.; J Neurochem; 1983 Jan; 40(1); 215-219 |
| Rivett AJ, Eddy BJ, Roth JA; Contribution of sulfate conjugation, deamination, and O-methylation to metabolism of dopamine and norepinephrine in human brain.; J Neurochem; 1982 Oct; 39(4); 1009-1016 |
| Roth JA, Rivett AJ; Does sulfate conjugation contribute to the metabolic inactivation of catecholamines in humans?; Biochem Pharmacol; 1982 Oct; 31(19); 3017-3021 |
| Rivett AJ, Roth JA; Kinetic studies on the O-methylation of dopamine by human brain membrane-bound catechol O-methyltransferase.; Biochemistry; 1982 Apr; 21(8); 1740-1742 |
| Roth JA, Eddy BJ, Pearce LB, Mulder KM; Phenylhydrazine: selective inhibition of human brain type B monoamine oxidase.; Biochem Pharmacol; 1981 May; 30(9); 945-950 |
| Roth JA, Eddy BJ; Kinetic properties of membrane-bound and Triton X-100-solubilized human brain monoamine oxidase.; Arch Biochem Biophys; 1980 Nov; 205(1); 260-266 |
| Young JG, Cohen DJ, Waldo MC, Feiz R, Roth JA; Platelet monoamine oxidase activity in children and adolescents with psychiatric disorders.; Schizophr Bull; 1980 Jan; 6(2); 324-333 |
| Snyder AM, Hull EM, Roth JA; The effect of maternal progesterone injections on fetal development of brain monoamine oxidase of rats.; Brain Res; 1979 Jul; 170(1); 194-197 |
| Roth JA; Benzylhydrazine--a selective inhibitor of human and rat brain monoamine oxidase.; Biochem Pharmacol; 1979 Mar; 28(6); 729-732 |
| Roth JA, Whittemore RM, Shakarjian MP, Eddy BJ; Inhibition of human brain type A and B monoamine oxidase by chloropromazine and metabolites.; Commun Psychopharmacol; 1979 Jan; 3(4); 235-243 |
| Franz JR, Hull EM, Snyder AM, Roth JA; The effect of maternal progesterone on brain monoamine oxidase activity of neonatal rats.; Brain Res; 1978 Dec; 158(2); 397-406 |
| Young JG, Cohen DJ, Roth JA; Association between platelet monoamine oxidase activity and hematocrit in childhood autism.; Life Sci; 1978 Aug; 23(8); 797-806 |
| Roth JA, Feor K; Deamination of dopamine and its 3-O-methylated derivative by human brain monoamine oxidase.; Biochem Pharmacol; 1978 Jan; 27(11); 1606-1608 |
| Roth JA; Inhibition of human brain type B monoamine oxidase by tricyclic psychoactive drugs.; Mol Pharmacol; 1978 Jan; 14(1); 164-171 |
| Roth JA, Venter JC; Predominance of the B form of monoamine oxidase in cultured vascular intimal endothelial cells.; Biochem Pharmacol; 1978 Jan; 27(19); 2371-2373 |
| Cohen DJ, Young JG, Roth JA; Platelet monoamine oxidase in early childhood autism.; Arch Gen Psychiatry; 1977 May; 34(5); 534-537 |
| Roth JA, Breakefield XO, Castiglione CM; Monoamine oxidase and catechol-O-methyltransferase activities in cultured human skin fibroblasts.; Life Sci; 1976 Dec; 19(11); 1705-1710 |
| Roth JA; Multiple forms of monoamine oxidase and their interaction with tricyclic psychomimetic drugs.; Gen Pharmacol; 1976 Dec; 7(6); 381-386 |
| Roth JA; Evidence for a single catalytic binding site on human brain type B monoamine oxidase.; J Neurochem; 1976 Nov; 27(5); 1107-1112 |
| Roth JA, Young JG, Cohen DJ; Platelet monoamine oxidase activity in children and adolescents.; Life Sci; 1976 May; 18(9); 919-924 |
| Roth JA, Gillis CN; Multiple forms of amine oxidase in perfused rabbit lung.; J Pharmacol Exp Ther; 1975 Sep; 194(3); 537-544 |
| Roth JA; Inhibition of rabbit monoamine oxidase by doxepin and related drugs.; Life Sci; 1975 Apr; 16(8); 1309-1319 |
| Gillis CN, Roth JA, Baker KR; Evidence for different forms of monoamine oxidase in perfused rabbit lung.; Chest; 1975 Feb; 67(2 Sup); 26-28 |
| Roth JA, Gillis CN; Inhibition of rabbit mitochondrial monoamine oxidase by iprindole.; Biochem Pharmacol; 1975 Jan; 24(1); 151-152 |
| Roth JA, Gillis CN; Some structural requirements for inhibition of type A and B forms of rabbit monoamine oxidase by tricyclic psychoactive drugs.; Mol Pharmacol; 1975 Jan; 11(1); 28-35 |
| Roth JA, Gillis CN; Deamination of beta-phenylethylamine by monoamine oxidase--inhibition by imipramine.; Biochem Pharmacol; 1974 Sep; 23(18); 2537-2545 |
| Roth JA, Gillis CN; Inhibition of lung, liver and brain monoamine oxidase by imipramine and desipramine.; Biochem Pharmacol; 1974 Mar; 23(6); 1138-1140 |
| Norman BJ, Roth JA, Neal RA; Effect of temperature on the mixed function oxidase-catalyzed metabolism of O,O-diethyl p-nitrophenyl phosphorothionate (parathion).; Toxicol Appl Pharmacol; 1973 Oct; 26(2); 203-208 |
| Roth JA; |
| Garrick MD, Singleton ST, Vargas F, Kuo HC, Zhao L, Knöpfel M, Davidson T, Costa M, Paradkar P, Roth JA, Garrick LM; DMT1: which metals does it transport?; Biol Res; 39(1); 79-85 |
| Kung MP, Nickerson P, Sansone FM, Olson J, Kostyniak P, Adolf M, Roth J; Effect of chronic exposure to hexachlorophene on rat brain cell specific marker enzymes.; |
| Kung MP, Nickerson P, Sansone FM, Olson J, Kostyniak P, Adolf M, Lein PJ, Roth J; Effect of short-term exposure to hexachlorophene on rat brain cell specific marker enzymes.; |
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