Dr. Sanjay Sethi
Medicine
Veterans Hospital

Phone: (716) 834-9200
Email: ssethi@buffalo.edu


OFFICE LOCATIONS

VA Medical Center
3495 Bailey Ave
Buffalo NY, 14215

Phone: 862-7874
Fax: 862-6526
Contact: Cookie Thurston
Email: sethi.sanjay@buffalo.va.gov
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SPECIALTIES

Pulmonary & Critical Care Medicine


EDUCATION

1984 Bachelor of Medicine/Bachelor of Science, Maulana Azad Medical College, Delhi, India


PUBLICATIONS

Schwingel JM, Edwards KJ, Cox AD, Masoud H, Richards JC, St Michael F, Tekwe CD, Sethi S, Murphy TF, Campagnari AA; Use of Moraxella catarrhalis lipooligosaccharide mutants to identify specific oligosaccharide epitopes recognized by human serum antibodies.; Infect Immun; 2009 Oct; 77(10); 4548-4558
Novotny LA, Adams LD, Kang DR, Wiet GJ, Cai X, Sethi S, Murphy TF, Bakaletz LO; Epitope mapping immunodominant regions of the PilA protein of nontypeable Haemophilus influenzae (NTHI) to facilitate the design of two novel chimeric vaccine candidates.; Vaccine; 2009 Aug;
LaFontaine ER, Snipes LE, Bullard B, Brauer AL, Sethi S, Murphy TF; Identification of domains of the Hag/MID surface protein recognized by systemic and mucosal antibodies in adults with chronic obstructive pulmonary disease following clearance of Moraxella catarrhalis.; Clin Vaccine Immunol; 2009 May; 16(5); 653-659
Gaschler GJ, Skrtic M, Zavitz CC, Lindahl M, Onnervik PO, Murphy TF, Sethi S, Stämpfli MR; Bacteria challenge in smoke-exposed mice exacerbates inflammation and skews the inflammatory profile.; Am J Respir Crit Care Med; 2009 Apr; 179(8); 666-675
Sethi S, Murphy TF; Infection in the pathogenesis and course of chronic obstructive pulmonary disease.; N Engl J Med; 2008 Nov; 359(22); 2355-2365
Cholon DM, Cutter D, Richardson SK, Sethi S, Murphy TF, Look DC, St Geme JW; Serial isolates of persistent Haemophilus influenzae in patients with chronic obstructive pulmonary disease express diminishing quantities of the HMW1 and HMW2 adhesins.; Infect Immun; 2008 Aug;
Sethi S, Wrona C, Eschberger K, Lobbins P, Cai X, Murphy TF; Inflammatory profile of new bacterial strain exacerbations of chronic obstructive pulmonary disease.; Am J Respir Crit Care Med; 2008 Mar; 177(5); 491-497
Sethi S; Optimizing antibiotic therapy for acute exacerbations of COPD.; International Journal of COPD; 2008;
Murphy TF, Brauer AL, Eschberger K, Lobbins P, Grove L, Cai X, Sethi S; Pseudomonas aeruginosa in Chronic Obstructive Pulmonary Disease.; Am J Respir Crit Care Med; 2008 Jan;
Sethi S; Treating and preventing Infections.; Clinical management of chronic obstructive pulmonary disease; 2008;
Sethi S, Wrona C, Eschberger K, Lobbins P, Cai X, Murphy TF; Inflammatory Profile of New Bacterial Strain Exacerbations of Chronic Obstructive Pulmonary Disease.; Am J Respir Crit Care Med; 2007 Dec;
Sethi S, File T., Dagan R.; Acute exacerbations of chronic bronchitis: diagnosis and therapy.; Journal of Respiratory Diseases; 2007 Oct;
Anzueto A, Sethi S, Martinez FJ; Exacerbations of chronic obstructive pulmonary disease.; Proc Am Thorac Soc; 2007 Oct; 4(7); 554-564
Malley R, Lipsitch M, Bogaert D, Thompson CM, Hermans P, Watkins AC, Sethi S, Murphy TF; Serum antipneumococcal antibodies and pneumococcal colonization in adults with chronic obstructive pulmonary disease.; J Infect Dis; 2007 Sep; 196(6); 928-935
Sethi S, Sethi R, Eschberger K, Lobbins P, Cai X, Grant BJ, Murphy TF; Airway bacterial concentrations and exacerbations of chronic obstructive pulmonary disease.; Am J Respir Crit Care Med; 2007 Aug; 176(4); 356-361
Sethi S, Blasi F.; Antibiotics allergy in a COPD patient with frequent bacterial exacerbations.; Clinical Challenges in COPD; 2007;
Sethi S; Book chapter on Bacteria, Chronic Obstructive Pulmonary Disease; Chronic Obstructive Pulmonary Disease; 2007;
Sethi S; Bronchoscopic Valor in Exacerbations of Chronic Bronchitis A Tale of Bugs and Drugs; Journal of Bronchology; 2007; 14(3); 137-139
Murphy TF, Brauer AL, Sethi S, Kilian M, Cai X, Lesse AJ; Haemophilus haemolyticus: a human respiratory tract commensal to be distinguished from Haemophilus influenzae.; J Infect Dis; 2007 Jan; 195(1); 81-89
Fernaays MM, Lesse AJ, Sethi S, Cai X, Murphy TF; Differential genome contents of nontypeable Haemophilus influenzae strains from adults with chronic obstructive pulmonary disease.; Infect Immun; 2006 Jun; 74(6); 3366-3374
Niederman M.S., Anzueto A., Sethi S, Choudhri S., Kureishi A., Haverstock D., Perroncel R.; Eradication of H. influenzae in AECB: A pooled analysis of moxifloxacin phase III trials compared with macrolide agents.; Respiratory Medicine; 2006 Mar; 174(1); 31-40
Berenson CS, Maloney J., Grove L., Wrona C., Sethi S; Impaired Alveolar Macrophage Response to Haemophilus Antigens in Chronic Obstructive Lung Disease.; Journal of Respiratory and Critical Care Medicine; 2006 Mar; 174(1); 31-40
Sethi S, Maloney J., Grove L., Wronta C.T., Berenson CS; Airway inflammation and bronchial bacterial colonization in ex-smokers with COPD.; American Journal of Respiratory and Critical Care Medicine; 2006; 173(9); 991-998
Sethi S; Co-infection in exacerbations of COPD: A new frontier.; Chest; 2006; 129(2); 223-224
Murphy TF, Brauer A., Sethi S, Kilian M., Cai X., Lesse A; Haemophilus hemolyticus: a human respiratory tract commensal to be distinguished from Haemophilus influenzae.; Journal of Infectious Disease; 2006 Jan; 195(1); 81-89
Adlowitz D., Kirkham, C., Sethi S, Murphy TF; Human Serum and Mucosal Antibody Responses to Outer Membrane Protein G1b of Moraxella catarrhalis in Chronic Obstructive Pulmonary Disease.; FEMS Immunology; 2006; 46(1); 139-146
Berenson CS, Garlipp M.A., Grove L.L., Maloney J., Sethi S; Impaired phagocytosis of nontypeable Haemophilus influenzae by human alveolar macrophages in chronic obstructive pulmonary disease.; Journal of Infectious Disease; 2006; 194(10); 1375-1384
Look D.C., Chin C.L., Manzel L.J., Lehman E.E., Humlicek A.L., Shi L., Starner T.D., Denning G.M., Murphy TF, Sethi S; Modulation of airway inflammation by Haemophilus influenzae isolates associated with chronic obstructive pulmonary disease exacerbation.; Proceedings of the American Thoracic Society; 2006; 3(6); 482-483
Veeramachaneni S., Sethi S; Pathogenesis of bacterial exacerbations of COPD.; COPD: Journal of Chronic Obstructive Pulmonary Disease; 2006; 3(2); 109-1116
Eldika, N., Sethi S; Role of Nontypeable Haemophilus influenzae in exacerbations and progression of COPD.; Current Opinion in Pulmonary Medicine; 2006; 12(2); 118-124
Chin CL, Manzel LJ, Lehman EE, Humlicek AL, Shi L, Starner TD, Denning GM, Murphy TF, Sethi S, Look DC; Haemophilus influenzae from patients with chronic obstructive pulmonary disease exacerbation induce more inflammation than colonizers.; Am J Respir Crit Care Med; 2005 Jul; 172(1); 85-91
Murphy TF, Brauer AL, Grant BJ, Sethi S; Moraxella catarrhalis in chronic obstructive pulmonary disease: burden of disease and immune response.; Am J Respir Crit Care Med; 2005 Jul; 172(2); 195-199
Murphy TF, Brauer A., Grant BJ, Sethi S; Moraxella catarrhalis in chronic obstructive pulmonary disease: burden of disease, dynamics of carriage and immune responses; American Journal of Respiratory and Critical Care Medicine; 2005 Jul; 172(2); 195-199
Sethi S; Moxifloxacin for the treatment of acute exacerbations of chronic obstructive pulmonary disease.; Clinical Infectious Diseases; 2005 Jul; 15(41); S177-S185
Murphy TF, Kirkham C, Sethi S, Lesse AJ; Expression of a peroxiredoxin-glutaredoxin by Haemophilus influenzae in biofilms and during human respiratory tract infection.; FEMS Immunol Med Microbiol; 2005 Apr; 44(1); 81-89
Sethi S, Murphy TF; RSV infection--not for kids only.; N Engl J Med; 2005 Apr; 352(17); 1810-1812
Sethi S, Anzueto A, Farrell D.J.; Antibiotic activity of telithromycin and comparators against bacterial pathogens isolated from 3,043 patients with acute exacerbation of chronic bronchitis.; Annals of Clinical Microbiology and Antimicrobials; 2005 Mar; 4(1); 5-5
Murphy TF, Brauer, A.L., Adler, B., Sethi S; Antigenic specificity of the mucosal antibody response to Moraxella catarrhalis in chronic obstructive pulmonary disease.; Infection and Immunity; 2005; 73(12); 8161-8166
Chin C.L., Manzel L.J., Lehman E.E., Humlicek, A.L., Shi L., Starner T.D., Denning G.M., Murphy TF, Sethi S, Look D.C.; Haemophilus influenzae from patients with COPD exacerbation induce more inflammation than colonizers.; American Journal of Respiratory and Critical Care Medicine; 2005; 172; 85-91
Adlowitz D., Sethi S, Adler B., Cullen, P., Murphy TF; Human Antibody Response to Outer Membrane Protein G1a, a Lipoprotein of Moraxella catarrhalis.; Infection and Immunity; 2005; 73(10); 6601-6607
Murphy TF, Brauer A.L., Aebi C., Sethi S; Identification of surface antigens of Moraxella catarrhalis as targets of human serum antibody responses in chronic obstructive pulmonary disease.; Infection and Immunity; 2005; 73(6); 3471-3478
Berenson CS, Murphy TF, Wrona, C.T., Sethi S; Outer membrane protein P6 of nontypeable Haemophilus influenzae is a potent and selective inducer of human macrophage cytokines; Infection and Immunity; 2005; 73(5); 2728-2735
Sethi S; Pathogenesis and treatment of acute exacerbations of COPD.; Seminars in Respiratory and Critical Care Medicine; 2005; 26(2); 192-203
Sethi S, Murphy TF; RSV infection: not for kids only; New England Journal of Medicine; 2005; 352(17); 1810-1812
Sethi S, Breton J., Wynne B.; The efficacy and safety of pharmacokinetically enhanced amoxicillin/clavulanate, 2000/125mg twice daily for 5 days, versus amoxicillin/clavulanate, 875/125mg twice daily for 7 days in the treatment of acute exacerbations of chronic bronchitis; Antimicrobial Agents and Chemotherapy; 2005; 49(1); 153-160
Sethi S, Murphy TF; Acute exacerbations of chronic bronchitis: new developments concerning microbiology and pathophysiology--impact on approaches to risk stratification and therapy.; Infect Dis Clin North Am; 2004 Dec; 18(4); 861-882
Sethi S; Musculoskeletal effects of chronic obstructive pulmonary disease: prevalent,linked, but ignored.; Am J Respir Crit Care Med; 2004 Dec; 170(12); 1267-1268
Sethi S, File TM; Managing patients with recurrent acute exacerbations of chronic bronchitis: a common clinical problem.; Curr Med Res Opin; 2004 Oct; 20(10); 1511-1521
Sethi S, Fogarty C, Fulambarker A; A randomized, double-blind study comparing 5 days oral gemifloxacin with 7days oral levofloxacin in patients with acute exacerbation of chronic bronchitis.; Respir Med; 2004 Aug; 98(8); 697-707
Murphy TF, Brauer AL, Schiffmacher AT, Sethi S; Persistent colonization by Haemophilus influenzae in chronic obstructive pulmonary disease.; Am J Respir Crit Care Med; 2004 Aug; 170(3); 266-272
Sethi S; New developments in the pathogenesis of acute exacerbations of chronic obstructive pulmonary disease.; Curr Opin Infect Dis; 2004 Apr; 17(2); 113-119
Sethi S, Wrona C, Grant BJ, Murphy TF; Strain-specific immune response to Haemophilus influenzae in chronic obstructive pulmonary disease.; Am J Respir Crit Care Med; 2004 Feb; 169(4); 448-453
Sethi S; Bacteria in exacerbations of COPD: Phenomenon or epiphenomenon; Proceedings of the American Thoracic Society; 2004; 1; 109-114
Sethi S; Gatifloxacin in community-acquired respiratory tract infection.; Expert Opin Pharmacother; 2003 Oct; 4(10); 1847-1855
Sethi S, Dagan, R.; Acute exacerbations of chronic bronchitis: Diagnosis and therapy; Respiratory Diseases; 2003; 24(6); 257-263
MURPHY TF; Horizontal transfer of the gene encoding outer membrane protein P2 of nontypeable Haemophilus influenzae in a patient with chronic obstructive pulmonary disease.; Journal of Infectious Diseases; 2003 Jan; 188; 114-117
MURPHY TF; Human immune response to outer membrane protein CD of Moraxella catarrhalis in adults with chronic obstructive pulmonary disease.; Infection and Immunity; 2003; 71; 1288-1294
Sethi S; The role of antibiotics in acute exacerbations of chronic obstructive pulmonary disease; Current Infectious Disease Reports; 2003; 5; 9-15
Niederman MS, Sethi S, Martinez F; Acute exacerbations of chronic obstructive pulmonary disease.; Ann Intern Med; 2002 Apr; 136(7); 556-558
Abe Y, Murphy TF, Sethi S, Faden HS, Dmochowski J, Harabuchi Y, Thanavala YM; Lymphocyte proliferative response to P6 of Haemophilus influenzae is associated with relative protection from exacerbations of chronic obstructive pulmonary disease.; Am J Respir Crit Care Med; 2002 Apr; 165(7); 967-971
Sethi S; Bacterial pneumonia. Managing a deadly complication of influenza in older adults with comorbid disease.; Geriatrics; 2002 Mar; 57(3); 56-61
Hiltke TJ, Sethi S, Murphy TF; Sequence stability of the gene encoding outer membrane protein P2 of nontypeable Haemophilus influenzae in the human respiratory tract.; J Infect Dis; 2002 Mar; 185(5); 627-631
Bakri F, Brauer AL, Sethi S, Murphy TF; Systemic and mucosal antibody response to Moraxella catarrhalis after exacerbations of chronic obstructive pulmonary disease.; J Infect Dis; 2002 Mar; 185(5); 632-640
Sethi S; Acute exacerbations of COPD: A "multi-pronged" approach; Respiratory Diseases; 2002; 23; 217-225
Murphy TF, Sethi S; Chronic obstructive pulmonary disease: Role of bacteria and guide to antibacterial selection in the older patient; Drugs and Aging; 2002; 19; 761-775
Sethi S; Efficacy of antibiotics in acute exacerbations: A review of the literature; Consultant; 2002; 42; S13-S19
Murphy TF, Sethi S, Hill SL, Stockley RA; Inflammatory markers in bacterial exacerbations of COPD.; Am J Respir Crit Care Med; 2002 Jan; 165(1); 132-132
Sethi S, Evans N, Grant BJ, Murphy TF; New strains of bacteria and exacerbations of chronic obstructive pulmonary disease.; New England Journal of Medicine; 2002; 347(7); 465-471
Sethi S, Murphy TF; Bacterial infection in chronic obstructive pulmonary disease in 2000: a state-of-the-art review.; Clin Microbiol Rev; 2001 Apr; 14(2); 336-363
Obaji, A., & Sethi S.; Acute exacerbations of chronic bronchitis: What role the new fluoroquinolones?; Drugs and Aging; 2001 Jan; 18; 1-11
Sethi S.; Antibiotics and acute exacerbation of COPD; Advance for Managers of Respiratory Care; 2001 Jan; 10(8); 28-31
Sethi,S./author of chapter Editors: Voelkel, N.F. & MacNee, W. Publisher: B.C. Decker, Inc.; Bacterial Infection; Book Chapter in Chronic Obstructive Lung Disease; 2001;
Fendrick, A.M., Saint, S., Brook, I., Jacobs, M.R., Pelton, S., Sethi S; Diagnosis and treatment of upper repiratory tract infections in the primary care setting; Clinical Therapeutics; 2001 Jan; 23; 1683-1706
Sheikh, S., & Sethi S.; Management of infectious excerbation of COPD; Home Health Care Consultant; 2001 Jan; 8; 21-27
Sethi S, Muscarella K, Evans N, Klingman KL, Grant BJ, Murphy TF; Airway inflammation and etiology of acute exacerbations of chronic bronchitis.; Chest; 2000 Dec; 118(6); 1557-1565
Sethi S, Murphy TF; Chronic obstructive pulmonary disease.; N Engl J Med; 2000 Dec; 343(26); 1969-1970
Sethi S; Pericolo di infiammazione. Le infezioni broncopolmonari; Ricera Roche (Italian); 2000 Dec;
Murphy TF, Sethi S, Niederman MS; The role of bacteria in exacerbations of COPD. A constructive view.; Chest; 2000 Jul; 118(1); 204-209
Sethi S; Bacterial infection and the pathogenesis of COPD.; Chest; 2000 May; 117(5 Sup); 286-291
Sethi S; Infectious etiology of acute exacerbations of chronic bronchitis.; Chest; 2000 May; 117(5 Sup); 380-385
Sethi S., Muscarella, K.A., Evans, N., Klingman, K.L., & Murphy, T.F.; Acute bacterial exacerbations of COPD are associated with greater airway inflammation than non-bacterial exacerbations; Chest; 2000 Jan; 118; 1557-1565
Murphy TF, Kirkham C, DeNardin E, Sethi S; Analysis of antigenic structure and human immune response to outer membrane protein CD of Moraxella catarrhalis.; Infect Immun; 1999 Sep; 67(9); 4578-4585
Murphy TF, Sethi S, Klingman KL, Brueggemann AB, Doern GV; Simultaneous respiratory tract colonization by multiple strains of nontypeable haemophilus influenzae in chronic obstructive pulmonary disease: implications for antibiotic therapy.; J Infect Dis; 1999 Aug; 180(2); 404-409
Sethi S; Infectious exacerbations of chronic bronchitis: diagnosis and management.; J Antimicrob Chemother; 1999 Mar; 43 Su; 97-105
Sethi S; Etiology & management of infections in COPD; Clinical Pulmonary Medicine; 1999 Jan; 6(6); 327-332
Sethi S; Is chronic bronchitis an infectious disease?; Mediguide to Pulmonary Medicine; 1998; 5(1);
Sethi S; Management of acute exacerbations of chronic bronchitis; Infectious Diseases in Clinical Practice; 1998; 7; S300-S308
Sethi S; The etiology of AECB. What role does infection play?; Postgraduate Medicine; 1998;
Yi K, Sethi S, Murphy TF; Human immune response to nontypeable Haemophilus influenzae in chronic bronchitis.; J Infect Dis; 1997 Nov; 176(5); 1247-1252
Sethi S, Surface JM, Murphy TF; Antigenic heterogeneity and molecular analysis of CopB of Moraxella (Branhamella) catarrhalis.; Infect Immun; 1997 Sep; 65(9); 3666-3671
Bhushan R, Kirkham C, Sethi S, Murphy TF; Antigenic characterization and analysis of the human immune response to outer membrane protein E of Branhamella catarrhalis.; Infect Immun; 1997 Jul; 65(7); 2668-2675
Murphy TF, Sethi S; A national strategy for research in chronic obstructive pulmonary disease.; JAMA; 1997 May; 277(20); 1596-1596
Sethi S, Murphy TF, Klingman KL; Diagnosis, epidemiology and pathogenesis of bacterial infections in the molecular era.; Clin Mol Pathol; 1996 Feb; 49(1); 1-7
Sethi S., Murphy, T.F., & Klingman, K.L.; Diagnosis, epidemiology & pathogenesis of bacterial infection in the molecular era; Clinical Pathology:Molecular Pathology; 1996 Jan; 49; M1-M7
Hsiao CB, Sethi S, Murphy TF; Outer membrane protein CD of Branhamella catarrhalis: sequence conservation in strains recovered from the human respiratory tract.; Microb Pathog; 1995 Oct; 19(4); 215-225
Sethi S, Hill SL, Murphy TF; Serum antibodies to outer membrane proteins (OMPs) of Moraxella (Branhamella) catarrhalis in patients with bronchiectasis: identification of OMP B1 as an important antigen.; Infect Immun; 1995 Apr; 63(4); 1516-1520
HSIAO C; Outer membrane protein CD of Branhamella catarrhalis: sequnce conservation in strains recovered from the human respiratory tract.; Microbial Pathogenesis; 1995; 19; 215-225
Murphy, T.F. & Sethi,S.; Preventing or treating COPD flare-ups; Emergency Medicine; 1993 Jan; 25; 65-68
Murphy TF, Sethi S; Bacterial infection in chronic obstructive pulmonary disease.; Am Rev Respir Dis; 1992 Oct; 146(4); 1067-1083
Sethi S, Sequeira W; Sparing effect of hemiplegia on scleroderma.; Ann Rheum Dis; 1990 Dec; 49(12); 999-1000



 
Dr. Sanjay Sethi
Dr. Sanjay Sethi