Dr. Satpal Singh
Pharmacology And Toxicology
Associate Professor
206 Cary Hall
Buffalo NY, 14214
Phone: (716) 829-2453
Fax: (716) 829-2801
Email: singhs@buffalo.edu
URL: http://www.buffalo.edu/~singhs/Site/Satpal_Singh.html

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EDUCATION

1980 Ph.D., Neuroscience, Molecular Biology
Tata Institute of Fundamental Research, Bombay, India
1973 Master of Science, Physics Honors, Physics
Punjab University, Chandigarh, India
Honors
1972 Bachelor of Science, Physics Honors, Physics
Punjab University, Chandigarh, India
Honors


PUBLICATIONS

Frolov RV, Slaughter MM, Singh S; Effects of celecoxib on ionic currents and spontaneous firing in rat retinal neurons.; Neuroscience; 2008 Jul; 154(4); 1525-1532
Frolov RV, Berim IG, Singh S; Inhibition of delayed rectifier potassium channels and induction of arrhythmia: a novel effect of celecoxib and the mechanism underlying it.; J Biol Chem; 2008 Jan; 283(3); 1518-1524
W. Liu, R. Gnanasambandam, J. Benjamin, G. Kaur, P. B. Getman, A. J. Siegel, R. D. Shortridge, and S. Singh; Mutations in Cytochrome c Oxidase Subunit VIa Cause Neurodegeneration and Motor Dysfunction in Drosophila; Genetics; 2007; 176(2);
Bhattacharya A, Lakhman SS, Singh S, Lakhman S; Modulation of L-type calcium channels in Drosophila via a pituitary adenylyl cyclase-activating polypeptide (PACAP)-mediated pathway.; J Biol Chem; 2004 Sep; 279(36); 37291-37297
Bhattacharya, A., Lakhman, S. S. and Singh, S.; Modulation of L-type Ca2+ Channels in Drosophila via a Pituitary Adenylyl Cyclase-activating Polypeptide (PACAP)-mediated pathway.; J. Biol. Chem.; 2004; 279; 37291-37297
Peri R, Triggle DJ, Singh S; Regulation of L-type calcium channels in pituitary GH(4)C(1) cells by depolarization.; J Biol Chem; 2001 Aug; 276(34); 31667-31673
R. Peri, Triggle D, Singh S; Regulation of L-type calcium channels in pituitary GH4C1 cells by depolarization; J. Biol. Chem; 2001 Jan; 276; 31667-31673
Peri R, Padmanabhan S, Rutledge A, Singh S, Triggle DJ; Permanently charged chiral 1,4-dihydropyridines: molecular probes of L-type calcium channels. Synthesis and pharmacological characterization of methyl(omega-trimethylalkylammonium) 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate iodi; J Med Chem; 2000 Jul; 43(15); 2906-2914
Chopra, M., Gu, G.-G. and Singh, S.; Mutations Affecting the Delayed Rectifier Potassium Current in Drosophila.; J. Neurogenetics; 2000; 14; 107-123
Hegde P, Gu GG, Chen D, Free SJ, Singh S; Mutational analysis of the Shab-encoded delayed rectifier K(+) channels in Drosophila.; J Biol Chem; 1999 Jul; 274(31); 22109-22113
Bhattacharya A, Gu GG, Singh S; Modulation of dihydropyridine-sensitive calcium channels in Drosophila by a cAMP-mediated pathway.; J Neurobiol; 1999 Jun; 39(4); 491-500
Singh S, Wu CF; Ionic currents in larval muscles of Drosophila.; Int Rev Neurobiol; 1999 Jan; 43; 191-220
Bhattacharya, A., Gu., G.-G. and Singh S.; Modulation of the Dihydropyridine-Sensitive Calcium Channels in Drosophila by a cAMP-Mediated Pathway.; J. Neurobiol.; 1999; 39; 491-500
Hegde, P., Gu, G-G., Chen, D., Free, S. J. and Singh, S.; Mutational Analysis of the Shab-encoded Delayed Rectifier K+ channels in Drosophila.; J. Biol. Chem.; 1999; 274; 22109-22113
Singh, A., and Singh, S.; Unmasking of a Novel Potassium Current in Drosophila by a Mutation and Drugs.; J. Neurosci.; 1999; 19; 6838-6843
Kraliz, D., Bhattacharya, A. and Singh, S.; Blockade of the Delayed Rectifier Potassium Current in Drosophila by Quinidine and Related Compounds.; J. Neurogenet.; 1998; 12; 25-39
Gu GG, Singh S; Modulation of the dihydropyridine-sensitive calcium channels in Drosophila by a phospholipase C-mediated pathway.; J Neurobiol; 1997 Sep; 33(3); 265-275
Gu G.-G. and Singh, S.; Modulation of the dihydropyridine-sensitive Ca2+ channels in Drosophila by a phospholipase C-mediated pathway.; J. Neurobiology.; 1997; 33; 265-275
Kraliz, D. and Singh, S.; Selective blockade of the delayed rectifier potassium current by tacrine in Drosophila.; J. Neurobiology; 1997; 32; 1-10
Gu GG, Singh S; Pharmacological analysis of heartbeat in Drosophila.; J Neurobiol; 1995 Nov; 28(3); 269-280
Gielow ML, Gu GG, Singh S; Resolution and pharmacological analysis of the voltage-dependent calcium channels of Drosophila larval muscles.; J Neurosci; 1995 Sep; 15(9); 6085-6093
Chopra M, Singh S; Developmental temperature selectively regulates a voltage-activated potassium current in Drosophila.; J Neurobiol; 1994 Feb; 25(2); 119-126
Singh S, Wu CF; Properties of potassium currents and their role in membrane excitability in Drosophila larval muscle fibers.; J Exp Biol; 1990 Sep; 152; 59-76
Komatsu A, Singh S, Rathe P, Wu CF; Mutational and gene dosage analysis of calcium-activated potassium channels in Drosophila: correlation of micro- and macroscopic currents.; Neuron; 1990 Feb; 4(2); 313-321
Wu CF, Tsai MC, Chen ML, Zhong Y, Singh S, Lee CY; Actions of dendrotoxin on K+ channels and neuromuscular transmission in Drosophila melanogaster, and its effects in synergy with K+ channel-specific drugs and mutations.; J Exp Biol; 1989 Nov; 147; 21-41
Singh, S.; A mutagenesis scheme for obtaining autosomal mutations in Drosophila; Ind. J. Exp. Biol.; 21; 635-636
Wu, C.-F., Tsai, M.-C., Chen, M.-L., Zhong, Y., Singh, S. and Lee, C.Y.; Actions of dendrotoxin on K+ channels and neuromuscular transmission in Drosophila melanogaster and its effects in synergy with K+ channel-specific drugs and mutations; J. Exp. Biol.; 147; 21-41
Neuweiler, G., Singh, S. and Sripathi, K.; Audiograms of a South Indian bat community; J. Comp. Physiol.; 154; 133-142
Schlegel, P., Jen, P.H.-S. and Singh, S.; Auditory spatial sensitivity of inferior collicular neurons of echolocating bats; Brain Res.; 456; 127-138
Kraliz, D., Bhattacharya, A. and Singh, S.; Blockade of the Delayed Rectifier Potassium Current in Drosophila by Quinidine and Related Compounds; J. Neurogenet.; 12; 25-39
Singh, A. and Wu, C.-F.; Complete separation of four potassium currents in Drosophila; Neuron; 2; 1325-1329
Chopra, M. and Singh, S.; Developmental temperature selectively regulates a voltage-activated potassium current in Drosophila; J. Neurobiol.; 25; 119-126
Singh, S., Bhandari, P., Chopra, M.J.S. and Guha, D.; Isolation of autosomal mutations in Drosophila melanogaster without setting up lines; Molec. Gen. Genet.; 208; 226-229
Gu G.-G. and Singh, S.; Modulation of the dihydropyridine-sensitive Ca2+ channels in Drosophila by a phospholipase C-mediated pathway; J. Neurobiology; 33; 265-275
Bhattacharya, A., Gu., G.-G. and Singh, S.; Modulation of the Dihydropyridine-Sensitive Calcium Channels in Drosophila by a cAMP-Mediated Pathway; J. Neurobiol.; 39; 491-500
Hedge, P., Gu, G-G., Chen, D., Free, S.J. and Singh, S.; Mutational Analysis of the Shab-encoded Delayed Rectifier K+ channels in Drosophila; J. Biol. Chem.; 274; 22109-22113
Komatsu, A., K., Singh, S., Rathe, P. and Wu, C.-F.; Mutational and gene-dosage analysis of calcium-activated potassium channels in Drosophila: Correlation of micro- and macroscopic currents; Neuron; 4; 313-321
Chopra, M., Gu, G.-G. and Singh, S; Mutations Affecting the Delayed Rectifier Potassium Current in Drosophila; J. Neurogenetics; 14; 107-123
Peri, R., Padmanabhan, S., Rutledge, A., Singh, A. and Triggle, D.J.; Permanently charged chiral 1,4-dihydropyridines: molecular probes of L-type calcium channels. Synthesis and Pharmacological characterization of methyl (w-trimethylalkylammonium) 1,4-dihydro-2,6-dimethyl-4-(3nitrophenyl)-3,5-pyridinedicarboxylate iodide,; J. Med. Chem.; 43; 2906-2914
Satpal Singh; Pharmacological analysis of heartbeat in Drosophila; j. Neurobiology; 28; 269-280
Singh, S. and Wu, C.-F.; Properties of potassium currents and their role in membrane excitability in Drosophila larval muscle fibers; J. Exp. Biol.; 152; 59-76
Singh, A.; Quantification of countercurrent distribution: from molecular partition to animal behavior; Biochem. Biophys. Res. Comm.; 196; 430-434
Gielow, M.L., Gu, G.-G. and Singh, S.S.; Resolution and pharmacological analysis of the voltage-dependent calcium channels of Drosophila larval muscles; J. Neuroscience; 15; 6085-6093
Kraliz, D. and Singh, S.; Selective Blockade of the delayed rectifier potassium current by tacrine in Drosophila; J. Neurobiology; 32; 1-10
Singh, S. and Siddiqi, O.; Torpid, a new sex linked temperature paralytic mutation in Drosophila melanogaster; Molec. Gen. Genet.; 181; 400-402
Schlegel, P. and Singh, S.; Unmasking in neurons of the inferior colliculus of Eptesicus fuscus with binaural stimulation; Hearing Res.; 10; 331-343
Singh, A. and Singh, S.; Unmasking of a Novel Potassium Current in Drosophila by a Mutation and Drugs; J. Neurosci.; 19; 6838-6843



 
Dr. Satpal Singh
Dr. Satpal Singh