Dr. Jeffrey Lackner Medicine 426 Erie County Medical Center Phone: (716) 898-5671 Email: lackner@buffalo.edu

OFFICE LOCATIONS

Erie County Medical Center Behavioral Medicine 462 Grider Street Buffalo NY, 14215 Contact: 716-898-5671 View map

SPECIALTIES

Gastroenterology Psychology-PhD

EXPERTISE

Behavioral Medicine My research is focused on showing how pscyhosocial factors (emotion, patient beleifs, relationships, coping style) influence the risk of onset, maintenance, and long term outcome of painful medical disorders, with a focus on irritable bowel syndrome and other fucntional medical illnesses

PUBLICATIONS

Lackner JM, Jaccard J, Krasner SS, Katz LA, Gudleski GD, Holroyd K; Self-administered cognitive behavior therapy for moderate to severe irritable bowel syndrome: clinical efficacy, tolerability, feasibility.; Clin Gastroenterol Hepatol; 2008 Aug; 6(8); 899-906

Fayyaz M, Lackner JM; Serotonin receptor modulators in the treatment of irritable bowel syndrome.; Ther Clin Risk Manag; 2008 Feb; 4(1); 41-48

Blanchard EB, Lackner JM, Jaccard J, Rowell D, Carosella AM, Powell C, Sanders K, Krasner S, Kuhn E; The role of stress in symptom exacerbation among IBS patients.; J Psychosom Res; 2008 Feb; 64(2); 119-128

Kloetzer, L., Gaman, A., McCallum, R., Koch, K.L., Sitrin MD, Chey, W.D., Lackner JM, Katz LA, Wilding, G.E., Parkman, H.P., Sarosiek, I., Miller, C., Saad, R.J., Rao, S.S., Semler, J.R., Hasler, W.L., Kuo, B.; Characterization of pressure patterns in distal colonic and rectal motility activity between healthy volunteers and patients with dyssynergic defecation using an ambulatory capsule, SmartPill. (published abstract); Gastroenterology; 2008; 134; A-281

Kuo B, McCallum RW, Koch KL, Sitrin MD, Wo JM, Chey WD, Hasler WL, Lackner JM, Katz LA, Semler JR, Wilding GE, Parkman HP; Comparison of gastric emptying of a nondigestible capsule to a radio-labelled meal in healthy and gastroparetic subjects.; Aliment Pharmacol Ther; 2008 Jan; 27(2); 186-196

Hasler, W.L., Saad, R.J., Rao, S.S., Katz LA, Parkman, H.P., Koch, K.L., McCallum, R., Kuo, B., Sarosiek, I., Sitrin MD, Lackner JM, Wilding, G.E., Miller, C., Semler, J.R., Chey, W.D.; Heightened motor activity measured by a wireless capsule in unprepared colons of patients with complaints of constipation: Relation to colon transit and IBS. (published abstract); Gastroenterology; 2008; 134; A-678

Lackner JM, Chey, W.D., Rao, S.S., Hasler, W.L,., Katz LA, Koch, K.L., Kuo, B., Lackner JM, Parkman, H.P., McCallum, R., Miller, C., Sarosiek, I., Semler, J.R., Sitrin MD, Wilding, G.E.; How well does stool form and stool frequency correlate with colonic and whole gut transit in healthy controls and constipated patients? (published abstract); Gastroenterology; 2008; 134; A-420

Lackner JM, Jaccard, J., Mangel, A.W., Naliboff, B.D.; Improving the adequacy of the adequate relief measure of clinical efficacy: A bayesian and conditional probability analysis of a multicenter RCT for IBS. (published abstract); Gastroenterology; 2008; 134; A-547-A-548

Lackner JM; Psychosocial aspects of functional GI disorders. (Book chapter in Textbook of Gastroenterology, 3rd ed.); ; 2008;

Lackner JM, Gudleski, G.D., Krasner, S.S., Powell, C., Katz LA; Rapid response to cognitive behavior therapy for irritable bowel syndrome: stepping Into a stepped care model of treatment delivery. (published abstract); Gastroenterology; 2008; 134; A-130

Kloetzer, L., Gaman, A., Napadow, V, McCallum, R., Koch, K., Sitrin MD, Chey, W.D., Lackner JM, Katz LA, Wilding, G.E., Parkman, H.P., Sarosiek, I., Smout, A.,, Hasler, W.L., Semler, J.R., Kuo, B.; Spectral analysis of contractile frequency in the ileum and proximal colon: Characterization of motility patterns using an ambulatory capsule, Smartpill. (published abstract); Gastroenterology; 2008; 134; A-676

Hasler, W.L., Rao, S.S., Koch, K.L., Sarosiek, I., McCallum, R, Lackner JM, Parkman, H.P, Chey, W.D., Saad, R.J, Kuo, B., Miller, C., Sitrin MD, Katz LA, Wilding, G.E, Semler, J.R.; Wireless capsule quantification of region-specific gastrocolonic response and sleep inhibition of colon motor activity in unprepared colons of humans with normal colon transit. (published abstract); Gastroenterology; 2008; 134; A-678

Lackner JM, Jaccard J, Krasner SS, Katz LA, Gudleski GD, Blanchard EB; How does cognitive behavior therapy for irritable bowel syndrome work? A mediational analysis of a randomized clinical trial.; Gastroenterology; 2007 Aug; 133(2); 433-444

Blanchard EB, Lackner JM, Sanders K, Krasner S, Keefer L, Payne A, Gudleski GD, Katz L, Rowell D, Sykes M, Kuhn E, Gusmano R, Carosella AM, Firth R, Dulgar-Tulloch L; A controlled evaluation of group cognitive therapy in the treatment of irritable bowel syndrome.; Behav Res Ther; 2007 Apr; 45(4); 633-648

Rao, S.S, McCallum, R., Parkman, H.P., Koch, K.L., Saad, R.J., Chey, W.D, DiBaise, J., Hutson, A., Semler, J.R., Sitrin MD, Lackner JM, Katz LA, Kuo, B.; A comparative study of SmartPill® and radioopaque markers for the assessment of colonic transit time in humans.(published abstract.); Gastroenterology; 2007; 132(sup 2); 458

Gaman, A, Hutson, A., Hwang, J., Stevens, K., Koch, K.L., Parkman, H.P., McCallum, R., Chey, W.D., Katz LA, Sitrin MD, Lackner JM, Hasler, W.L., Wo, J., Semler, J.R., Kuo, B.; A non-digestible device discriminates motility patterns with a luminal acidic pH change within the distal small bowel and proximal colon. (published abstract); Gastroenterology; 2007; 132(Sup 2); -459

Parkman, H.P., Hutson, A., Lackner JM, Katz LA, Sitrin MD, Kuo, B., McCallum, R., Chey, W.D., Hasler, W.L., Wo, J., Koch, K.L, Semler, J.R.; Assessment of symptoms associated with delayed gastric emptying of the SmartPill. (published abstract); Neurogastroenterology and Motility; 2007; 19; 248

Hasler, W.L., Coleski, R., Sarosiek, I., McCallum, R, Kuo, B., Parkman, H.P, Sitrin MD, Lackner JM, Katz LA, Koch, K.L., Wo, J., Chey, W.D, Hutson, A., Semler, J.R.; Colon transit and regional colon motor activity in diabetics with gastroparesis compared to healthy volunteers and diabetics with near normal gastric emptying. (published abstract); Gastroenterology; 2007 Jan; 132(2); 459

Sarosiek, I., Sarosiek, J., Rao, S., Parkman, H.P., Kuo, B., Lackner JM, Katz LA, Sitrin MD, Chey, W.D., Hasler, W.L., DiBaise, J., Wo, J., Koch, K.L., Semler, J.R., McCallum, R.; Comparisons of alimentary tract transit times among normal subjects from two multicenter trials using SmartPill wireless pH/pressure recording capsule: Its clinical implication. (published abstract); The American Journal of Gastroenterology; 2007; 102(Sup 2); s156-s174

Kloetzer, L., Gaman, A., Nojkov, B., Chey, W.D., Hwang, J., Stevens, K., Koch, K.L., Parkman, H.P., McCallum, R., Katz LA, Sitrin MD, Lackner JM, Hasler, W.L., Wo, J., Semler, J.R., Kuo, B.; Complete pH profiling of the gastrointestinal tract in healthy volunteers with an ambulatory pH capsule. (published abstract); Gastroenterology; 2007; 132(Supp); 461

Lackner JM; Controlling IBS the drug free way: A 10 step program for symptom relief.; ; 2007;

Rao, S, Kuo, B., Chey, W.D., DiBaise, J., Katz LA, Koch, K.L., Lackner JM, McCallum, R, Saad, R.J, Selover, K.,, Semler, J.R., Sitrin MD, Wilding, G.E, Parkman, H.P; Investigation of wireless capsule (SmartPill) for colonic transit: A comparative study with radiopaque markers in health and constipation. (published abstract); American Journal of Gastroenterology; 2007; 102(Sup 2); s498-s517

Reddymasu, S., Gaman, A., Sarosiek, I., Parkman, H.P., Hutson, A., Chey, W.D., Katz LA, Lackner JM, Koch, K.L., Semler, J.R., Kuo, B., McCallum, R.; Non-digestible capsule technology to measure amplitude and frequency characteristics of gastric contractions- comparison between healthy and gastroparetic subjects. (published abstract); Neurogastroenterology and Motility; 2007; 19; 429

Reddymasu, S, Sarosiek, I., Koch, K.L., Hasler, W.L., Lackner JM, Katz LA, Sitrin MD, Parkman, H.P., Wo, J., Chey, W.D., Semler, J.R., Hwang, J., Kuo, B., McCallum, R.; Non-digestible capsule technology to measure frequency of gastric contractions- comparison between healthy and gastroparetic subjects. (published abstract); Gastroenterology; 2007; 132(Sup 2); 677

Sarosiek, I., Reddymasu, S., Koch, K.L., Hasler, W.L,, Lackner JM, Katz LA, Sitrin MD, Parkman, H.P., Wo, J., Sarosiek, J, Chey, W.D., Semler, J.R., Kuo, B., McCallum, R.; Relationship between the frequency of gastric contractions and gastric emptying of a non-digestible solid in controls and gastroparetics using SmartPill pressure recording capsule: Its future clinical potential. (published abstract); Gastroenterology; 2007; 132(Sup 2); 378

Rao, S.S.,, Kuo, B., Chey, W.D., DiBaise, J, Katz LA, Koch, K.L., Lackner JM, McCallum, R., Saad, R.J., Selover, K., Semler, J.R., Sitrin MD, Wilding, G.E., Parkman, H.P.; Simultaneous assessment of colonic transit using wireless capsule (SmartPill) and radiopaque markers in healthy subjects and effects of gender. (published abstract); The American Journal of Gastroenterology; 2007; 102(Sup 2); s249-s271

Noe M., Epstein, L. H, Trevisan, M., Fisher, N., Lackner JM, Leddy, C,, Paluch, R.; The health improvement project (HIP): An intensive medical intervention for class III obesity and results of a pilot study. (published abstract); Obesity; 2007; 15; A-162

Morgiel J, Major L, Major B, Lackner JM, Nistor L; Advances and problems with TEM characterization of Cr/CrN multilayer coatings.; J Microsc; 2006 Sep; 223(Pt 3); 237-239

Lackner JM, Lou Coad M, Mertz HR, Wack DS, Katz LA, Krasner SS, Firth R, Mahl TC, Lockwood AH; Cognitive therapy for irritable bowel syndrome is associated with reduced limbic activity, GI symptoms, and anxiety.; Behav Res Ther; 2006 May; 44(5); 621-638

Lackner JM, Gudleski GD, Zack MM, Katz LA, Powell C, Krasner S, Holmes E, Dorscheimer K; Measuring health-related quality of life in patients with irritable bowel syndrome: can less be more?; Psychosom Med; 2006 Mar; 68(2); 312-320

Blanchard EB, Lackner JM, Gusmano R, Gudleski GD, Sanders K, Keefer L, Krasner S; Prediction of treatment outcome among patients with irritable bowel syndrome treated with group cognitive therapy.; Behav Res Ther; 2006 Mar; 44(3); 317-337

Sarosiek, I., Kock, K. L., Selover, K., Kuo, B., Parkman, H. P., Hasler, W. L., Wo, J. M., Sitrin MD, Chey, W. D.,, Lackner JM, D‘Andrea, D., McCallum, R. W.; A new non-scintigraphic method for measuring gastrointestinal transit in gastroparetic patients. (published abstract); Gastroenterology; 2006; 130; A-739

Lackner JM, Holroyd, K.A., Gudleski, G.D., Krasner, S.S., Katz LA, Powell, C., Sampeth, P.K., Firth, R.S., Yates, B.L; A randomized controlled trial of therapist-administered vs. minimal contact cognitive behavioral treatment for moderate to severe IBS. (published abstract); Gastroenterology; 2006; 130; A-78

Lackner JM, Jaccard, J., Krasner, S.S., Katz LA, Blanchard, E,B.; How does cognitive behavioral therapy for IBS work? A structural equation modeling analysis of results from a randomized controlled trial. (published abstract); Gastroenterology; 2006; 130; A-504

Lackner JM; Irritable bowel syndrome: case formulation from the perspective of a behavioral functional analytical mode. (Book chapter in Formulation and Treatment in Clinical Health Psychology.); ; 2006;

Parkman, H. P., Huston, A., Maurer, A. H., Knight, L. C., Kuo, B., Hasler, W. L, Chey, W. D.,, McCallum, R. W., Wo, J. M., Kock, K. L., Sitrin MD, Lackner JM, Semler, J.; Optimizing gastric emptying scintigraphy for the detection of gastroparesis. (published abstract); Gastroenterology; 2006; 130; A-507

Kuo, B, McCallum, R. W., Kock, K. L., Chey, W. D., Wo, J. M.,, Sitrin MD, Hasler, W.L., Lackner JM, Katz LA, Landrigan, B., Selover, K., Huston, A., Barthel, D., Semler, J., Parkman, H. P.; Smartpill, a novel ambulatory diagnostic test for measuring gastric emptying in health and disease. (published abstract); Gastroenterology; 2006; 130; A-434

Lackner JM, Quigley BM; Pain catastrophizing mediates the relationship between worry and pain suffering in patients with irritable bowel syndrome.; Behav Res Ther; 2005 Jul; 43(7); 943-957

Lackner JM, Gurtman MB; Patterns of interpersonal problems in irritable bowel syndrome patients: a circumplex analysis.; J Psychosom Res; 2005 Jun; 58(6); 523-532

Lackner JM, Jaccard J, Blanchard EB; Testing the sequential model of pain processing in irritable bowel syndrome: a structural equation modeling analysis.; Eur J Pain; 2005 Apr; 9(2); 207-218

Lackner JM, Blanchard, E. B, Krasner, S. S., Firth, R. S., Gudleski, G, Sanders, K, Keefer L., Katz, L, Carosella, A. M, Payne, A.; Are psychological treatments for IBS effective for the full spectrum of symptoms for which patients seek treatment: Results of a multisite randomized controlled study.(published abstract); Gastroenterology; 2005; 128(S-2); A-340

Bahadur, S., Sitrin MD, Kuo B., Viazis N., Semler J, Lackner JM; Assessment of upper GI. motility in healthy subjects using ambulant capsule technology. (published abstract); Gastroenterology; 2005; 128(S2); A 544

Kuo B., Urma D., Koch K,, Sitrin MD, Bahadur S., Lackner JM, Katz LA, Chey W., Chund G, Semler, J.R., Parkman H.; Correlation between gastric emptying times of an indigestible capsule and scintigraphic meal. (published abstract); Neurogastroenterology and Motility; 2005; 17; 622

Lackner JM; Is IBS a problem of emotion regulation?: A test of the level of emotional awareness model. (published abstract); Psychosomatic Medicine; 2005; 67(1); A-4

Urma D., Parkman H., Koch K., Sitrin MD, Bahadur S., Lackner JM, Katz LA, Chey W., Motott J., Semler J.R., Kuro B.; Postprandial small intestinal motility response recording with a wireless capsule technology. (published abstract); Neurogastroenterology and Motility; 2005; 17; 623

Lackner JM, Mesmer C, Morley S, Dowzer C, Hamilton S; Psychological treatments for irritable bowel syndrome: a systematic review and meta-analysis.; J Consult Clin Psychol; 2004 Dec; 72(6); 1100-1113

Lackner JM, Gurtman MB; Pain catastrophizing and interpersonal problems: a circumplex analysis of the communal coping model.; Pain; 2004 Aug; 110(3); 597-604

Lackner JM, Quigley BM, Blanchard EB; Depression and abdominal pain in IBS patients: the mediating role of catastrophizing.; Psychosom Med; 2004 May; 66(3); 435-441

Blanchard EB, Keefer L, Lackner JM, Galovski TE, Krasner S, Sykes MA; The role of childhood abuse in Axis I and Axis II psychiatric disorders and medical disorders of unknown origin among irritable bowel syndrome patients.; J Psychosom Res; 2004 Apr; 56(4); 431-436

Lackner JM, Lockwood A., Coad M.L., Mahl TC, Firth R., Mertz H., Katz LA, Krasner S., Wack D.S., Galantowicz P.; Alterations in GI Symptoms, Psychological Status and Brain Functioning Participation in Cognitive Behavioral Therapy for IBS. (abstract); Gastroenterology; 2004; 126; A477

Lackner JM, Lockwood, A., Coad, ML., Mahl TC, Firth, R, Mertz, H., Katz LA, Krasner, S, Wack, D, Galantowicz, P; Alterations in GI symptoms, psychological status, and brain function following participation in cognitive therapy for IBS. (Poster of Distinction).; Gastroenterology; 2004; 126(S2); A 477

Lackner JM, Gudleski GD, Blanchard EB; Beyond abuse: the association among parenting style, abdominal pain, and somatization in IBS patients.; Behav Res Ther; 2004 Jan; 42(1); 41-56

Lackner JM; Chronic Pain (book chapter in Adult Psychopathology Case Studies); ; 2004;

Lackner JM, Quigely, B., Blanchard, E.B.; Depression and abdominal pain in irritable bowel syndrome: The mediating role of catastrophizing. (published abstract); Gastroenterology; 2004; 126(S2); A-479

Janotta M, Vogt F, Voraberger HS, Waldhauser W, Lackner JM, Stotter C, Beutl M, Mizaikoff B; Direct analysis of oxidizing agents in aqueous solution with attenuated total reflectance mid-infrared spectroscopy and diamond-like carbon protected waveguides.; Anal Chem; 2004 Jan; 76(2); 384-391

Lackner JM; Functional Gastrointestinal Disorders - book chapter in Encyclopedia of Health Psychology.; ; 2004;

Lackner JM, Mahl TC, Wilding G.E.; IBS Patients’ Response to Abdominal Pain: Too Sensitive, Too Tough or Both? (abstract); Gastroenterology; 2004; 126; A481

Lackner JM, Mahl TC, Wilding, E.; IBS patients’ response to abdominal pain: Too sensitive, too tough, or both? (published abstract); Gastroenterology; 2004; 126(S2); A480

Lackner JM, Lockwood A., Mahl TC, Krasner S., Katz LA; Prospective Changes in Blood Flow, Anxiety and GI Symptoms in Irritable Bowel in Patients Treated with Cognitive Therapy. (abstract - . Presented at the 38th Annual Convention of the Association for Advancement of Behavior Therapy. November 2004. ); ; 2004;

Shipherd JC, Beck JG, Hamblen JL, Lackner JM, Freeman JB; A preliminary examination of treatment for posttraumatic stress disorder in chronic pain patients: a case study.; J Trauma Stress; 2003 Oct; 16(5); 451-457

Granger CV, Lackner JM, Kulas M, Russell CF; Outpatients with low back pain: an analysis of the rate per day of pain improvement that may be expected and factors affecting improvement.; Am J Phys Med Rehabil; 2003 Apr; 82(4); 253-260

Lackner JM, Gudleski, G., Blanchard, E.B.; Beyond abuse: association among parenting behavior, abdominal pain, and somatization in IBS patients. (published abstract); Gastroenterology; 2003; 124(S1);

Lackner JM, Gurtman, M.; Interpersonal factors associated with irritable bowel syndrome. (published abstract); Gastroenterology; 2003; 124(S1); A-539

Lackner JM; Irritable bowel syndrome (book chapter - Handbook of health psychology).; ; 2003;

Granger, C.V., Lackner JM; Outpatients with low back pain: An analysis of the rate per day of pain and factors affecting improvement (book chapter - Advances in Physical and Rehabilitation Medicine.; ; 2003;

Lackner JM, Morley, S.M., Dowzer, C.M., Mesmer, C., Hamilton, S.; Systematic review and meta analysis of randomized clinical trials of psychological treatments for irritable bowel syndrome. (published abstract); Gastroenterology; 2003; 124(S1); A-529

Lackner JM, Jaccard, J.; Testing the Sequential Model of Pain Processing in Irritable Bowel Syndrome: A structural equation modeling analysis. (published abstract); Gastroenterology; 2003; 124(S1); A-529

Beck JG, Freeman JB, Shipherd JC, Hamblen JL, Lackner JM; Specificity of Stroop interference in patients with pain and PTSD.; J Abnorm Psychol; 2001 Nov; 110(4); 536-543

Fessler R.D., Linn, R.T., Granger, C.V., Olson, K, Ostrow, G, Hartney, M, Lackner JM, Gutterman, L.R., Hopkins, L.N.; Improved cognition following carotid artery stent placement. (published abstract); Journal of Neurosurgery; 2001; 94(180A);

Lackner JM, Carosella AM; The relative influence of perceived pain control, anxiety, and functional self efficacy on spinal function among patients with chronic low back pain.; Spine; 1999 Nov; 24(21); 2254-2260

Carosella AM, Lackner JM, Feuerstein M; Factors associated with early discharge from a multidisciplinary work rehabilitation program for chronic low back pain.; Pain; 1994 Apr; 57(1); 69-76

GRANTS

May 2008 to May 2015 Self Administered CBT for IBS: A Multisite Trial National Institutes of Health – NIDDK Jeffrey Lackner $8,800,000

June 2007 to June 2007 The development and manufacture of miniature electronics and related sensor technologies used in capsule-based gastrointestinal diagnostic products. New York State Office of Science, Technology and Academic Research Jeffrey Lackner $60,000

January 2007 to December 2008 A Multicenter, Randomized, Placebo-Controlled, Double-Blinded Study of the Efficacy and Safety of Lubiprostone in Patients with Opioid-Induced Bowel Dysfunction, Sucampo/Takeda Pharmaceuticals Michael Sitrin, Jeffrey Lackner $30,000

January 2007 to December 2008 Procurement of fasting blood samples for use in the development of a gastrointestinal disease test panel. Prometheus Laboratories Michael Sitrin, Jeffrey Lackner $12,750

January 2006 to December 2007 A randomized, double-blind, placebo-controlled, parallel-group, multicenter study to evaluate the efficacy and safety of DNK333 25 mg b.i.d. given orally for 4 weeks in female patients with Diarrhea-predominant Irritable Bowel Syndrome (IBS-D) Novartis Pharmaceutical Michael Sitrin, Jeffrey Lackner $45,000

January 2005 to December 2011 1: A pilot study for the evaluation of treatments for severe obesity for BCBS of WNY members; 2: A pragmatic clinical evaluation of treatments for severe obesity for BCBS of WNY members Blue Cross Blue Shield of Western New York Jeffrey Lackner $5,034,791

January 2004 to December 2007 Development of limited contact CBT for IBS. National Institutes of Health – NIDDK Jeffrey Lackner $357,000

January 2004 to December 2007 Smartpill Development Project New York State Office of Science, Technology and Academic Research Jeffrey Lackner $500,000

June 2003 to May 2004 SmartPill: Device for Portable Noninvasive Motility Recording New York State Center for Advanced Technology in Biomedical and Bioengineering University at Buffalo Jeffrey Lackner $85,000

February 2002 to October 2003 Functional neuroanatomy of visceral pain in patients with irritable bowel syndrome, A controlled prospective study of self management training. University at Buffalo Interdisciplinary Research and Creative Funds Jeffrey Lackner $50,000

January 2002 to December 2002 Improving the efficiency and effectiveness of medical management of irritable bowel syndrome. Novartis Pharmaceuticals Jeffrey Lackner $32,000

January 1999 to December 2005 Cognitive therapy for IBS: Outcome, Process, and Prediction(R0154211) National Institutes of Health - NIDDK Jeffrey Lackner $1,800,000

January 1990 to December 1990 A two-year study of dieting, stress, social resources and coping among adolescents. Walter S. Rosenberry III Charitable Fund Jeffrey Lackner $10,000

Quantitative Progressive Exercise Treatment for TBI and Post Concussion Syndrome. US Army Medical Research and Material Command Leddy, John, Jeffrey Lackner $1,567,000