Dr. Michael Sitrin
Medicine
Chair, Division of Gastroenterology
Veterans Hospital

Phone: (716) 834-9200


OFFICE LOCATIONS

Erie County Medical Center
462 Grider Street
Buffalo NY, 14215

Phone: 716-898-3391
Contact: Tracy Brown
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UBMD Internal Medicine
3980 Sheridan Drive
6th Floor
Amherst NY, 14226

Phone: 716-882-6544
Fax: 716-882-6833
Contact: Jill Balbuzoski
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Insurance Accepted
CIGNA HealthCare
Community Blue (HMO)
Empire
Fidelis
GHI
Independent Health Association (HMO)
Magnacare
Medicare
NYS Medicaid
North American Administrators
Nova
Preferred Care
Railroad Medicare
United Healthcare
Univera Health Care (HMO)
VA Western New York
3495 Bailey Ave
Buffalo NY, 14215

Phone: 862-8634
Fax: 862-8632
Contact: Donna Donahue
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SPECIALTIES

Gastroenterology


EDUCATION

1974 M.D., Medicine
Harvard Medical School
1970 Zoology, Zoology
University of Michigan
high honors


PUBLICATIONS

Samuel S, Sitrin MD; Vitamin D's role in cell proliferation and differentiation.; Nutr Rev; 2008 Oct; 66(10 Su); 116-124
Hasler WL, Coleski R, Chey WD, Koch KL, McCallum RW, Wo JM, Kuo B, Sitrin MD, Katz LA, Hwang J, Semler JR, Parkman HP; Differences in intragastric pH in diabetic vs. idiopathic gastroparesis: relation to degree of gastric retention.; Am J Physiol Gastrointest Liver Physiol; 2008 Jun; 294(6); 1384-1391
Kloetzer, L., Gaman, A., McCallum, R., Koch, K.L., Sitrin MD, Chey, W.D., Lackner JM, Katz LA, Wilding, G.E., Parkman, H.P., Sarosiek, I., Miller, C., Saad, R.J., Rao, S.S., Semler, J.R., Hasler, W.L., Kuo, B.; Characterization of pressure patterns in distal colonic and rectal motility activity between healthy volunteers and patients with dyssynergic defecation using an ambulatory capsule, SmartPill. (published abstract); Gastroenterology; 2008; 134; A-281
Kuo B, McCallum RW, Koch KL, Sitrin MD, Wo JM, Chey WD, Hasler WL, Lackner JM, Katz LA, Semler JR, Wilding GE, Parkman HP; Comparison of gastric emptying of a nondigestible capsule to a radio-labelled meal in healthy and gastroparetic subjects.; Aliment Pharmacol Ther; 2008 Jan; 27(2); 186-196
Yen R., Pomakov, O., Mehboob S, Sitrin MD; Ethnic Differences in Findings on Screening Colonoscopy. (Abstract # S1113); Gastroenterology; 2008; 103(S1);
Hasler, W.L., Saad, R.J., Rao, S.S., Katz LA, Parkman, H.P., Koch, K.L., McCallum, R., Kuo, B., Sarosiek, I., Sitrin MD, Lackner JM, Wilding, G.E., Miller, C., Semler, J.R., Chey, W.D.; Heightened motor activity measured by a wireless capsule in unprepared colons of patients with complaints of constipation: Relation to colon transit and IBS. (published abstract); Gastroenterology; 2008; 134; A-678
Lackner JM, Chey, W.D., Rao, S.S., Hasler, W.L,., Katz LA, Koch, K.L., Kuo, B., Lackner JM, Parkman, H.P., McCallum, R., Miller, C., Sarosiek, I., Semler, J.R., Sitrin MD, Wilding, G.E.; How well does stool form and stool frequency correlate with colonic and whole gut transit in healthy controls and constipated patients? (published abstract); Gastroenterology; 2008; 134; A-420
Raddymasu S., Sarosiek I., Parkman H.P., Koch K.L., Sitrin MD, Wo J.M., Hasler W.L., Katz LA, Chey W.D., Semler J.R., Kuo B., McCallum R.; Non-digestible capsule technology to measure gastric motility – comparison between healthy controls and gastroparetic patients with a normal gastric emptying study. (published abstract); Gastroenterology; 2008; 134; A629
Kloetzer, L., Gaman, A., Napadow, V, McCallum, R., Koch, K., Sitrin MD, Chey, W.D., Lackner JM, Katz LA, Wilding, G.E., Parkman, H.P., Sarosiek, I., Smout, A.,, Hasler, W.L., Semler, J.R., Kuo, B.; Spectral analysis of contractile frequency in the ileum and proximal colon: Characterization of motility patterns using an ambulatory capsule, Smartpill. (published abstract); Gastroenterology; 2008; 134; A-676
Hasler, W.L., Rao, S.S., Koch, K.L., Sarosiek, I., McCallum, R, Lackner JM, Parkman, H.P, Chey, W.D., Saad, R.J, Kuo, B., Miller, C., Sitrin MD, Katz LA, Wilding, G.E, Semler, J.R.; Wireless capsule quantification of region-specific gastrocolonic response and sleep inhibition of colon motor activity in unprepared colons of humans with normal colon transit. (published abstract); Gastroenterology; 2008; 134; A-678
Yen R., Pomakov O., Abdal-Raheem A., Sitrin MD, Mehboob S; Ethnic Differences in Findings on Screening Colonoscopy. (Abstract # 1196); American J. of Gastro; 2007 Sep;
Fayyaz M, Mehboob S, Andersen V., Sitrin MD; Extended Octreotide Suppression test to determine hormone responsiveness of multiple Type I Gastric Carcinoid Tumors. (Case Report); Digestive Diseases and Sciences 2007; 2007 Jun; 52(6); 1579-1585
Fayyaz M, Mehboob S, Andersen V, Sitrin MD; Extended octreotide suppression test to determine hormone responsiveness of multiple type I gastric carcinoid tumors.; Dig Dis Sci; 2007 Jun; 52(6); 1579-1585
Rao, S.S, McCallum, R., Parkman, H.P., Koch, K.L., Saad, R.J., Chey, W.D, DiBaise, J., Hutson, A., Semler, J.R., Sitrin MD, Lackner JM, Katz LA, Kuo, B.; A comparative study of SmartPill® and radioopaque markers for the assessment of colonic transit time in humans.(published abstract.); Gastroenterology; 2007; 132(sup 2); 458
Gaman, A, Hutson, A., Hwang, J., Stevens, K., Koch, K.L., Parkman, H.P., McCallum, R., Chey, W.D., Katz LA, Sitrin MD, Lackner JM, Hasler, W.L., Wo, J., Semler, J.R., Kuo, B.; A non-digestible device discriminates motility patterns with a luminal acidic pH change within the distal small bowel and proximal colon. (published abstract); Gastroenterology; 2007; 132(Sup 2); -459
Parkman, H.P., Hutson, A., Lackner JM, Katz LA, Sitrin MD, Kuo, B., McCallum, R., Chey, W.D., Hasler, W.L., Wo, J., Koch, K.L, Semler, J.R.; Assessment of symptoms associated with delayed gastric emptying of the SmartPill. (published abstract); Neurogastroenterology and Motility; 2007; 19; 248
Hasler, W.L., Coleski, R., Sarosiek, I., McCallum, R, Kuo, B., Parkman, H.P, Sitrin MD, Lackner JM, Katz LA, Koch, K.L., Wo, J., Chey, W.D, Hutson, A., Semler, J.R.; Colon transit and regional colon motor activity in diabetics with gastroparesis compared to healthy volunteers and diabetics with near normal gastric emptying. (published abstract); Gastroenterology; 2007 Jan; 132(2); 459
Cheng H, Sitrin MD, Satchidanand SK, Novak JM; Colonic squamous cell carcinoma in ulcerative colitis: Report of a case and review of the literature.; Can J Gastroenterol; 2007 Jan; 21(1); 47-50
Sarosiek, I., Sarosiek, J., Rao, S., Parkman, H.P., Kuo, B., Lackner JM, Katz LA, Sitrin MD, Chey, W.D., Hasler, W.L., DiBaise, J., Wo, J., Koch, K.L., Semler, J.R., McCallum, R.; Comparisons of alimentary tract transit times among normal subjects from two multicenter trials using SmartPill wireless pH/pressure recording capsule: Its clinical implication. (published abstract); The American Journal of Gastroenterology; 2007; 102(Sup 2); s156-s174
Kloetzer, L., Gaman, A., Nojkov, B., Chey, W.D., Hwang, J., Stevens, K., Koch, K.L., Parkman, H.P., McCallum, R., Katz LA, Sitrin MD, Lackner JM, Hasler, W.L., Wo, J., Semler, J.R., Kuo, B.; Complete pH profiling of the gastrointestinal tract in healthy volunteers with an ambulatory pH capsule. (published abstract); Gastroenterology; 2007; 132(Supp); 461
Rao, S, Kuo, B., Chey, W.D., DiBaise, J., Katz LA, Koch, K.L., Lackner JM, McCallum, R, Saad, R.J, Selover, K.,, Semler, J.R., Sitrin MD, Wilding, G.E, Parkman, H.P; Investigation of wireless capsule (SmartPill) for colonic transit: A comparative study with radiopaque markers in health and constipation. (published abstract); American Journal of Gastroenterology; 2007; 102(Sup 2); s498-s517
Reddymasu, S, Sarosiek, I., Koch, K.L., Hasler, W.L., Lackner JM, Katz LA, Sitrin MD, Parkman, H.P., Wo, J., Chey, W.D., Semler, J.R., Hwang, J., Kuo, B., McCallum, R.; Non-digestible capsule technology to measure frequency of gastric contractions- comparison between healthy and gastroparetic subjects. (published abstract); Gastroenterology; 2007; 132(Sup 2); 677
Cheng H., Nasser E., Khawam E., Andersen, V., Sitrin MD; Protein kinase C alpha and p21waf1 expression are increased in the remnant jejunum after ileal resection in the rat. (published abstract); Gastroenterology; 2007; 132; A711
Sarosiek, I., Reddymasu, S., Koch, K.L., Hasler, W.L,, Lackner JM, Katz LA, Sitrin MD, Parkman, H.P., Wo, J., Sarosiek, J, Chey, W.D., Semler, J.R., Kuo, B., McCallum, R.; Relationship between the frequency of gastric contractions and gastric emptying of a non-digestible solid in controls and gastroparetics using SmartPill pressure recording capsule: Its future clinical potential. (published abstract); Gastroenterology; 2007; 132(Sup 2); 378
Bhagat V., Andersen V., Sitrin MD; Role of the vitamin D receptor in vitamin D-mediated calbindin D(9k) expression in Caco-2 cells. (published abstract); Gastroenterology; 2007; 132; A584
Rao, S.S.,, Kuo, B., Chey, W.D., DiBaise, J, Katz LA, Koch, K.L., Lackner JM, McCallum, R., Saad, R.J., Selover, K., Semler, J.R., Sitrin MD, Wilding, G.E., Parkman, H.P.; Simultaneous assessment of colonic transit using wireless capsule (SmartPill) and radiopaque markers in healthy subjects and effects of gender. (published abstract); The American Journal of Gastroenterology; 2007; 102(Sup 2); s249-s271
Cheng H, Sitrin MD, Rani A; Angiomyolipoma in the colon.; Gastrointest Endosc; 2006 Sep; 64(3); 443-444
Sarosiek, I., Kock, K. L., Selover, K., Kuo, B., Parkman, H. P., Hasler, W. L., Wo, J. M., Sitrin MD, Chey, W. D.,, Lackner JM, D‘Andrea, D., McCallum, R. W.; A new non-scintigraphic method for measuring gastrointestinal transit in gastroparetic patients. (published abstract); Gastroenterology; 2006; 130; A-739
Rafiq S., Andersen V., Satchidanand K., Graves R., Sitrin MD; Increased sensitivity to carbon tetrachloride hepatotoxicity in the aP2DTA mouse model of acquired lipodystrophy and insulin resistance. (published abstract); Gastroenterology; 2006; 130; A22
Parkman, H. P., Huston, A., Maurer, A. H., Knight, L. C., Kuo, B., Hasler, W. L, Chey, W. D.,, McCallum, R. W., Wo, J. M., Kock, K. L., Sitrin MD, Lackner JM, Semler, J.; Optimizing gastric emptying scintigraphy for the detection of gastroparesis. (published abstract); Gastroenterology; 2006; 130; A-507
Hasler W.L., Parkman H.L., Hutson A., Chey W.D., Koch K.L., McCallum R.W., Wo J.M., Kuo B., Sitrin MD, Stevens K., Landrigan B., Semler J.R., Coleski R.; Postprandial gastric acids neutralization-reacidification measured with an ingested pH telemetry capsule: correlation with emptying of digestible and indigestible solids. (published abstract); Gastroenterology; 2006; 130; A408
Kuo, B, McCallum, R. W., Kock, K. L., Chey, W. D., Wo, J. M.,, Sitrin MD, Hasler, W.L., Lackner JM, Katz LA, Landrigan, B., Selover, K., Huston, A., Barthel, D., Semler, J., Parkman, H. P.; Smartpill, a novel ambulatory diagnostic test for measuring gastric emptying in health and disease. (published abstract); Gastroenterology; 2006; 130; A-434
Fayyaz M, Mehboob S, Andersen V., Sitrin MD; Extended Octreotide Suppression test to determine hormone responsiveness in a patient with multiple gastric Carcinoid Tumors.(Abstract # 100); American J. of Gastro; 2005 Sep;
Bolt MJ, Cao LP, Kong J, Sitrin MD, Li YC; Vitamin D receptor is required for dietary calcium-induced repression of calbindin-D9k expression in mice.; J Nutr Biochem; 2005 May; 16(5); 286-290
Rafiq S, Hameer H, Sitrin MD; Ganglioneuromatous polyposis associated with juvenile polyps and a tubular adenoma.; Dig Dis Sci; 2005 Mar; 50(3); 506-508
Bahadur, S., Sitrin MD, Kuo B., Viazis N., Semler J, Lackner JM; Assessment of upper GI. motility in healthy subjects using ambulant capsule technology. (published abstract); Gastroenterology; 2005; 128(S2); A 544
Kuo B., Urma D., Koch K,, Sitrin MD, Bahadur S., Lackner JM, Katz LA, Chey W., Chund G, Semler, J.R., Parkman H.; Correlation between gastric emptying times of an indigestible capsule and scintigraphic meal. (published abstract); Neurogastroenterology and Motility; 2005; 17; 622
Urma D., Parkman H., Koch K., Sitrin MD, Bahadur S., Lackner JM, Katz LA, Chey W., Motott J., Semler J.R., Kuro B.; Postprandial small intestinal motility response recording with a wireless capsule technology. (published abstract); Neurogastroenterology and Motility; 2005; 17; 623
Bolt MJ, Liu W, Qiao G, Kong J, Zheng W, Krausz T, Cs-Szabo G, Sitrin MD, Li YC; Critical role of vitamin D in sulfate homeostasis: regulation of the sodium-sulfate cotransporter by 1,25-dihydroxyvitamin D3.; Am J Physiol Endocrinol Metab; 2004 Oct; 287(4); 744-749
Cheng H, Cook M, Sitrin MD; Image of the month. Gallstone ileus.; Gastroenterology; 2004 Sep; 127(3); 705 1020-705 1020
Bolt MJ, Liu W, Qiao G, Kong J, Zheng W, Krausz T, Cs-Szabo G, Sitrin MD, Li YC; Critical Role of Vitamin D in Sulfate Homeostasis: Regulation of the Sodium-Sulfate Co-transporter by 1,25-Dihydroxyvitamin D3.; Am J Physiol Endocrinol Metab; 2004 May;
Khare S, Cerda S, Wali RK, von Lintig FC, Tretiakova M, Joseph L, Stoiber D, Cohen G, Nimmagadda K, Hart J, Sitrin MD, Boss GR, Bissonnette M; Ursodeoxycholic acid inhibits Ras mutations, wild-type Ras activation, and cyclooxygenase-2 expression in colon cancer.; Cancer Res; 2003 Jul; 63(13); 3517-3523
Chung PY, Sitrin MD, Te HS; Serum phosphorus levels predict clinical outcome in fulminant hepatic failure.; Liver Transpl; 2003 Mar; 9(3); 248-253
Wali RK, Kong J, Sitrin MD, Bissonnette M, Li YC; Vitamin D receptor is not required for the rapid actions of 1,25-dihydroxyvitamin D3 to increase intracellular calcium and activate protein kinase C in mouse osteoblasts.; J Cell Biochem; 2003 Mar; 88(4); 794-801
Barak N, Wall-Alonso E, Cheng A, Sitrin MD; Use of bioelectrical impedance analysis to predict energy expenditure of hospitalized patients receiving nutrition support.; JPEN J Parenter Enteral Nutr; 2003 Jan; 27(1); 43-46
Wali RK, Stoiber D, Nguyen L, Hart J, Sitrin MD, Brasitus T, Bissonnette M; Ursodeoxycholic acid inhibits the initiation and postinitiation phases of azoxymethane-induced colonic tumor development.; Cancer Epidemiol Biomarkers Prev; 2002 Nov; 11(11); 1316-1321
Chen A, Davis BH, Sitrin MD, Brasitus TA, Bissonnette M; Transforming growth factor-beta 1 signaling contributes to Caco-2 cell growth inhibition induced by 1,25(OH)(2)D(3).; Am J Physiol Gastrointest Liver Physiol; 2002 Oct; 283(4); 864-874
Barak N, Wall-Alonso E, Sitrin MD; Evaluation of stress factors and body weight adjustments currently used to estimate energy expenditure in hospitalized patients.; JPEN J Parenter Enteral Nutr; 2002 Jul; 26(4); 231-238
Cao LP, Bolt MJ, Wei M, Sitrin MD, Chun Li Y; Regulation of calbindin-D9k expression by 1,25-dihydroxyvitamin D(3) and parathyroid hormone in mouse primary renal tubular cells.; Arch Biochem Biophys; 2002 Apr; 400(1); 118-124
Barak N, Ehrenpreis ED, Harrison JR, Sitrin MD; Gastro-oesophageal reflux disease in obesity: pathophysiological and therapeutic considerations.; Obes Rev; 2002 Feb; 3(1); 9-15
Chung P.Y., Sitrin MD, Te H.S.; Serum hypophosphatemia is associated with hepatic recovery in fulminant hepatic failure. (published abstract.); Gastroenterology; 2002; 122; 19
Li YC, Bolt MJ, Cao LP, Sitrin MD; Effects of vitamin D receptor inactivation on the expression of calbindins and calcium metabolism.; Am J Physiol Endocrinol Metab; 2001 Sep; 281(3); 558-564
Barak N, Hart J, Sitrin MD; Enalapril-induced eosinophilic gastroenteritis.; J Clin Gastroenterol; 2001 Aug; 33(2); 157-158
Chen A., Bissonnette M., Sitrin MD, Brasitus T.A.; ERK, and its downstream target, Ets-1, are involved in the 1,25(OH)2D3 -induced inhibition of cell growth and stimulation of apoptosis in Caco-2 cells. (published abstract); Gastroenterology; 2001; 120(5); A665
Mustafi R., Cerda S.R., Sitrin MD, Brasitus T.A., Bissonnette M.; Protein kinase C-Zeta (PKC-?) Over-expression in Caco-2 cells inhibits anchorage-dependent and -independent proliferation while enhancing apoptosis. (published abstract); Gastroenterology; 2001; 120(5); 3586
Khare S, Wali R., Cerda S., Hart J,, Sitrin MD, Brasitus T., Bissonnette M; Ursodeoxycholic acid and an analogue of vitamin D inhibit COX-2 expression in AOM-induced colonic tumors and in HCA-7 Cells: Roles of C/EBP-? and VEGF. (published abstract); Gastroenterology; 2001; 120(5); 899
Wali R., Stoiber D., Hart J., Sitrin MD, Brasitus T., Bissonnette M.; Ursodeoxycholic acid inhibits tumor development during both AOM-induced colon tumor initiation and progression. (published abstract); Gastroenterology; 2001; 120(5); 1321
Samuel S., Alawneh A., Sitrin MD; HRP 12, the murine member of the highly conserved by enigmatic YERO57c/Yjgf/UK114 family, interacts with mitochondrial and secreted liver proteins in the yeast-based two-hybrid system. (published abstract); Gastroenterology; 2000; 134; A817
Khare S, Bissonnette M, Scaglione-Sewell B, Wali RK, Sitrin MD, Brasitus TA; 1,25-dihydroxyvitamin D3 and TPA activate phospholipase D in Caco-2 cells: role of PKC-alpha.; Am J Physiol; 1999 Apr; 276(4 Pt); 993-1004
Khare S, Bissonnette M, Wali R, Skarosi S, Boss GR, von Lintig FC, Scaglione-Sewell B, Sitrin MD, Brasitus TA; 1,25-dihydroxyvitamin D3 but not TPA activates PLD in Caco-2 cells via pp60(c-src) and RhoA.; Am J Physiol; 1999 Apr; 276(4 Pt); 1005-1015
Sitrin MD, Bissonnette M, Bolt MJ, Wali R, Khare S, Scaglione-Sewell B, Skarosi S, Brasitus TA; Rapid effects of 1,25(OH)2 vitamin D3 on signal transduction systems in colonic cells.; Steroids; 1999 Jan; 64(1-2); 137-142
Bolt MJ, Mailloux RJ, Rasenick MM, Wali RK, Skarosi S, Bissonnette M, Brasitus TA, Sitrin MD; Expression of G protein alpha subunits in normal rat colon and in azoxymethane-induced colonic neoplasms.; Gastroenterology; 1998 Dec; 115(6); 1494-1503
Berkelhammer C, Wood RJ, Sitrin MD; Inorganic phosphorus reduces hypercalciuria during total parenteral nutrition by enhancing renal tubular calcium absorption.; JPEN J Parenter Enteral Nutr; 1998 May; 22(3); 142-146
Khare S, Bolt MJ, Wali RK, Skarosi SF, Roy HK, Niedziela S, Scaglione-Sewell B, Aquino B, Abraham C, Sitrin MD, Brasitus TA, Bissonnette M; 1,25 dihydroxyvitamin D3 stimulates phospholipase C-gamma in rat colonocytes: role of c-Src in PLC-gamma activation.; J Clin Invest; 1997 Apr; 99(8); 1831-1841
Bothe A, Sitrin MD; Treatment decisions: opinions or data?; Nutr Clin Pract; 1996 Feb; 11(1); 3-4
Wali RK, Frawley BP, Hartmann S, Roy HK, Khare S, Scaglione-Sewell BA, Earnest DL, Sitrin MD, Brasitus TA, Bissonnette M; Mechanism of action of chemoprotective ursodeoxycholate in the azoxymethane model of rat colonic carcinogenesis: potential roles of protein kinase C-alpha, -beta II, and -zeta.; Cancer Res; 1995 Nov; 55(22); 5257-5264
Wali RK, Bissonnette M, Khare S, Hart J, Sitrin MD, Brasitus TA; 1 alpha,25-Dihydroxy-16-ene-23-yne-26,27-hexafluorocholecalciferol, a noncalcemic analogue of 1 alpha,25-dihydroxyvitamin D3, inhibits azoxymethane-induced colonic tumorigenesis.; Cancer Res; 1995 Jul; 55(14); 3050-3054
Bissonnette M, Wali RK, Hartmann SC, Niedziela SM, Roy HK, Tien XY, Sitrin MD, Brasitus TA; 1,25-Dihydroxyvitamin D3 and 12-O-tetradecanoyl phorbol 13-acetate cause differential activation of Ca(2+)-dependent and Ca(2+)-independent isoforms of protein kinase C in rat colonocytes.; J Clin Invest; 1995 May; 95(5); 2215-2221
Wali RK, Bissonnette M, Jiang K, Niedziela SM, Khare S, Roy HK, Sitrin MD, Brasitus TA; 1,25-Dihydroxyvitamin D3 stimulates the phosphorylation of two acidic membrane proteins of 42,000 and 48,000 daltons in rat colonocytes: an effect modulated by vitamin D status.; J Cell Physiol; 1995 Feb; 162(2); 172-180
Bissonnette M, Tien XY, Niedziela SM, Hartmann SC, Frawley BP, Roy HK, Sitrin MD, Perlman RL, Brasitus TA; 1,25(OH)2 vitamin D3 activates PKC-alpha in Caco-2 cells: a mechanism to limit secosteroid-induced rise in [Ca2+]i.; Am J Physiol; 1994 Sep; 267(3 Pt); 465-475
Khare S, Wilson D, Wali RK, Tien XY, Bissonnette M, Niedziela SM, Bolt MJ, Sitrin MD, Brasitus TA; Guanylin activates rat colonic particulate guanylate cyclase.; Biochem Biophys Res Commun; 1994 Sep; 203(3); 1432-1437
Khare S, Tien XY, Wilson D, Wali RK, Bissonnette BM, Scaglione-Sewell B, Sitrin MD, Brasitus TA; The role of protein kinase-C alpha in the activation of particulate guanylate cyclase by 1 alpha,25-dihydroxyvitamin D3 in CaCo-2 cells.; Endocrinology; 1994 Jul; 135(1); 277-283
Frawley BP, Tien XY, Hartmann SC, Wali RK, Niedziela SM, Davidson NO, Sitrin MD, Brasitus TA, Bissonnette M; TPA causes divergent responses of Ca(2+)-dependent and Ca(2+)-independent isoforms of PKC in the nuclei of Caco-2 cells.; Biochim Biophys Acta; 1994 Jun; 1222(2); 301-305
Khare S, Tien XY, Wilson D, Wali RK, Bissonnette BM, Sitrin MD, Brasitus TA; Vitamin D status modulates rat colonic M3 muscarinic receptor characteristics and coupling to guanylate cyclase.; FEBS Lett; 1994 Jun; 347(1); 27-30
Halline AG, Davidson NO, Skarosi SF, Sitrin MD, Tietze C, Alpers DH, Brasitus TA; Effects of 1,25-dihydroxyvitamin D3 on proliferation and differentiation of Caco-2 cells.; Endocrinology; 1994 Apr; 134(4); 1710-1717
Khare S, Wilson DM, Tien XY, Dudeja PK, Wali RK, Sitrin MD, Brasitus TA; 1,25-Dihydroxycholecalciferol rapidly activates rat colonic particulate guanylate cyclase via a protein kinase C-dependent mechanism.; Endocrinology; 1993 Nov; 133(5); 2213-2219
Tien XY, Katnik C, Qasawa BM, Sitrin MD, Nelson DJ, Brasitus TA; Characterization of the 1,25-dihydroxycholecalciferol-stimulated calcium influx pathway in CaCo-2 cells.; J Membr Biol; 1993 Nov; 136(2); 159-168
Tien XY, Brasitus TA, Qasawa BM, Norman AW, Sitrin MD; Effect of 1,25(OH)2D3 and its analogues on membrane phosphoinositide turnover and [Ca2+]i in Caco-2 cells.; Am J Physiol; 1993 Jul; 265(1 Pt); 143-148
Jacoby RF, Bolt MJ, Dolan ME, Otto G, Dudeja P, Sitrin MD, Brasitus TA; Supplemental dietary calcium fails to alter the acute effects of 1,2-dimethylhydrazine on O6-methylguanine, O6-alkylguanine-DNA alkyltransferase and cellular proliferation in the rat colon.; Carcinogenesis; 1993 Jun; 14(6); 1175-1179
Davidson NO, Ifkovits CA, Skarosi SF, Hausman AM, Llor X, Sitrin MD, Montag A, Brasitus TA; Tissue and cell-specific patterns of expression of rat liver and intestinal fatty acid binding protein during development and in experimental colonic and small intestinal adenocarcinomas.; Lab Invest; 1993 Jun; 68(6); 663-675
Bolt MJ, Bissonnette BM, Wali RK, Hartmann SC, Brasitus TA, Sitrin MD; Characterization of phosphoinositide-specific phospholipase C in rat colonocyte membranes.; Biochem J; 1993 May; 292 (; 271-276
Heber D, Halsted CH, Brooks CM, Chesney RW, DiGirolamo M, Heimburger DC, Hensrud DD, Mark DA, Sitrin MD, Tillman HH; Biennial survey of physician clinical-nutrition training programs.; Am J Clin Nutr; 1993 Apr; 57(4); 463-469
Wali RK, Baum CL, Bolt MJ, Brasitus TA, Sitrin MD; 1,25-dihydroxyvitamin D3 inhibits Na(+)-H+ exchange by stimulating membrane phosphoinositide turnover and increasing cytosolic calcium in CaCo-2 cells.; Endocrinology; 1992 Sep; 131(3); 1125-1133
Wali RK, Bolt MJ, Tien XY, Brasitus TA, Sitrin MD; Differential effect of 1,25-dihydroxycholecalciferol on phosphoinositide turnover in the antipodal plasma membranes of colonic epithelial cells.; Biochem Biophys Res Commun; 1992 Sep; 187(2); 1128-1134
Wali RK, Baum CL, Sitrin MD, Bolt MJ, Dudeja PK, Brasitus TA; Effect of vitamin D status on the rapid actions of 1,25-dihydroxycholecalciferol in rat colonic membranes.; Am J Physiol; 1992 Jun; 262(6 Pt); 945-953
Sitrin MD; Nutrition support in inflammatory bowel disease.; Nutr Clin Pract; 1992 Apr; 7(2); 53-60
Bolt MJ, Jensen WE, Sitrin MD; Metabolism of 25-hydroxyvitamin D3 in rats: low-calcium diet vs. calcitriol infusion.; Am J Physiol; 1992 Mar; 262(3 Pt); 359-367
Teegarden D, Meredith SC, Sitrin MD; Determination of the affinity of vitamin D metabolites to serum vitamin D binding protein using assay employing lipid-coated polystyrene beads.; Anal Biochem; 1991 Dec; 199(2); 293-299
Sitrin MD, Halline AG, Abrahams C, Brasitus TA; Dietary calcium and vitamin D modulate 1,2-dimethylhydrazine-induced colonic carcinogenesis in the rat.; Cancer Res; 1991 Oct; 51(20); 5608-5613
Leichtmann GA, Bengoa JM, Bolt MJ, Sitrin MD; Intestinal absorption of cholecalciferol and 25-hydroxycholecalciferol in patients with both Crohn's disease and intestinal resection.; Am J Clin Nutr; 1991 Sep; 54(3); 548-552
Llor X, Jacoby RF, Teng BB, Davidson NO, Sitrin MD, Brasitus TA; K-ras mutations in 1,2-dimethylhydrazine-induced colonic tumors: effects of supplemental dietary calcium and vitamin D deficiency.; Cancer Res; 1991 Aug; 51(16); 4305-4309
Dudeja PK, Wali RK, Klitzke A, Sitrin MD, Brasitus TA; Correction of enhanced Na(+)-H+ exchange of rat small intestinal brush-border membranes in streptozotocin-induced diabetes by insulin or 1,25-dihydroxycholecalciferol.; J Clin Invest; 1991 May; 87(5); 1755-1762
Wali RK, Baum CL, Bolt MJ, Dudeja PK, Sitrin MD, Brasitus TA; Down-regulation of protein kinase C activity in 1,2-dimethylhydrazine-induced rat colonic tumors.; Biochim Biophys Acta; 1991 Mar; 1092(1); 119-123
Leichtmann GA, Sitrin MD; Update on trace elements.; Compr Ther; 1991 Jan; 17(1); 42-48
Wali RK, Dudeja PK, Bolt MJ, Sitrin MD, Brasitus TA; Correction of abnormal small intestinal cytosolic protein kinase C activity in streptozotocin-induced diabetes by insulin therapy.; Biochem J; 1990 Dec; 272(3); 653-658
Baum CL, Wali RK, Sitrin MD, Bolt MJ, Brasitus TA; 1,2-Dimethylhydrazine-induced alterations in protein kinase C activity in the rat preneoplastic colon.; Cancer Res; 1990 Jul; 50(13); 3915-3920
Wali RK, Baum CL, Sitrin MD, Brasitus TA; 1,25(OH)2 vitamin D3 stimulates membrane phosphoinositide turnover, activates protein kinase C, and increases cytosolic calcium in rat colonic epithelium.; J Clin Invest; 1990 Apr; 85(4); 1296-1303
Janghorbani M, Rockway S, Mooers CS, Roberts EM, Ting BT, Sitrin MD; Effect of chronic selenite supplementation on selenium excretion and organ accumulation in rats.; J Nutr; 1990 Mar; 120(3); 274-279
Brasitus TA, Sitrin MD; Intestinal malabsorption syndromes.; Annu Rev Med; 1990 Jan; 41; 339-347
Bolt MJ, Stellaard F, Sitrin MD, Paumgartner G; Serum unconjugated bile acids in patients with small bowel bacterial overgrowth.; Clin Chim Acta; 1989 Apr; 181(1); 87-101
Knowles JB, Cusson G, Smith M, Sitrin MD; Pulmonary deposition of calcium phosphate crystals as a complication of home total parenteral nutrition.; JPEN J Parenter Enteral Nutr; 1989 Mar; 13(2); 209-213
Brasitus TA, Dudeja PK, Bolt MJ, Sitrin MD, Baum C; Dietary triacylglycerol modulates sodium-dependent D-glucose transport, fluidity and fatty acid composition of rat small intestinal brush-border membrane.; Biochim Biophys Acta; 1989 Feb; 979(2); 177-186
Berkelhammer CH, Wood RJ, Sitrin MD; Acetate and hypercalciuria during total parenteral nutrition.; Am J Clin Nutr; 1988 Dec; 48(6); 1482-1489
Wood RJ, Sitrin MD, Rosenberg IH; Effect of phosphorus on endogenous calcium losses during total parenteral nutrition.; Am J Clin Nutr; 1988 Sep; 48(3); 632-636
Sitrin MD, Bengoa JM; Intestinal absorption of cholecalciferol and 25-hydroxycholecalciferol in chronic cholestatic liver disease.; Am J Clin Nutr; 1987 Dec; 46(6); 1011-1015
Derus CL, Levinson DJ, Bowman B, Bengoa JM, Sitrin MD; Altered fractional excretion of uric acid during total parenteral nutrition.; J Rheumatol; 1987 Oct; 14(5); 978-981
Sitrin MD, Lieberman F, Jensen WE, Noronha A, Milburn C, Addington W; Vitamin E deficiency and neurologic disease in adults with cystic fibrosis.; Ann Intern Med; 1987 Jul; 107(1); 51-54
Sitrin MD, Berkelhammer C.H., Vereault D.V.; Comparison of the calciuretic effect of methionine and Na2SO4 in the rat. (published abstract); Clinical Research; 1987; 35; 799A
Berkelhammer C.H., Wood R.J., Rosenberg I.H., Sitrin MD; Mechanism for reduction of TPN induced hypercalciuria by phosphate: Evidence against the role of parathyroid hormone. (published abstract); Journal of Parenteral and Enteral Nutrition; 1987; 11; 95
Sitrin MD, Bolt M.J.G., Ford H.; Mechanism of transport of vitamin D3 palmitate in plasma. (published abstract); Clinical Research; 1987; 35; 371A
Teegarden D., Meredith S.C., Sitrin MD; Modeling of 25 hydroxyvitamin D binding to rat serum vitamin D binding protein. (published abstract); Federation Proceedings; 1987; 46; 603
Kushner RF, Shapir J, Sitrin MD; Endoscopic, radiographic, and clinical response to prolonged bowel rest and home parenteral nutrition in Crohn's disease.; JPEN J Parenter Enteral Nutr; 1986 Nov; 10(6); 568-573
Wood RJ, Sitrin MD, Cusson GJ, Rosenberg IH; Reduction of total parenteral nutrition-induced urinary calcium loss by increasing the phosphorus in the total parenteral nutrition prescription.; JPEN J Parenter Enteral Nutr; 1986 Mar; 10(2); 188-190
Kushner RF, Sitrin MD; Metabolic acidosis. Development in two patients receiving a potassium-sparing diuretic and total parenteral nutrition.; Arch Intern Med; 1986 Feb; 146(2); 343-345
Schraut W.H., Lee K.K.W., Sitrin MD, Moynihan H.L.; A comparison of the outcome after end to end vs. end to side ileo colonic anastomosis. (published abstract); Association for Acad Surgery; 1986;
Berkelhammer C.H., Wood R.J., Rosenberg I.H., Sitrin MD; Alkalinization with acetate reduces hypercalciuria during total parenteral nutrition. (published abstract); Clinical Research; 1986; 34; 792A
Wood R.J., Sitrin MD, Rosenberg I.H.; Effect of phosphate on urinary calcium excretion in normal and thyroparathyroidectomized rats receiving total parenteral nutrition. (published abstract.); Clinical Research; 1986; 34; 807A
Sitrin MD; Hepatic histology in long term total parenteral nutrition (TPN). (published abstract); Gastroenterology; 1986; 90; 1737
Teegarden D., Meredith S.C., Sitrin MD; Partial purification of rat enterocyte cytosolic 25 hydroxyvitamin D (25 OHD) binding protein. (published abstract); Federation Proceedings; 1986; 45; 834
Schraut W.H., Lee K.K.W., Sitrin MD; Recipient growth and nutritional status following transplantation of segmental small bowel allografts. (published abstract); Association for Acad Surgery; 1986;
Schraut W.H., Lee K.K.W., Sitrin MD; Small bowel transplantation in the young rat permitting normal growth and maturation. (published abstract); ESSR; 1986;
Sitrin MD, Pollack KL, Bolt MJ; Intestinal absorption of 1,25-dihydroxyvitamin D3 in the rat.; Am J Physiol; 1985 Jun; 248(6 Pt); 718-725
Wood RJ, Bengoa JM, Sitrin MD, Rosenberg IH; Calciuretic effect of cyclic versus continuous total parenteral nutrition.; Am J Clin Nutr; 1985 Mar; 41(3); 614-619
Rosenberg IH, Bengoa JM, Sitrin MD; Nutritional aspects of inflammatory bowel disease.; Annu Rev Nutr; 1985 Jan; 5; 463-484
Bengoa JM, Hanauer SB, Sitrin MD, Baker AL, Rosenberg IH; Pattern and prognosis of liver function test abnormalities during parenteral nutrition in inflammatory bowel disease.; Hepatology; 1985 Jan; 5(1); 79-84
Sitrin MD, Jensen W.E.; Transfer of vitamin D metabolites and other fat soluble vitamins from chylomicrons to serum. (published abstract); Clinical Research; 1985; 33; 277a
Wood R.J., Sitrin MD, Cusson G.J., Rosenberg I.H.; Urinary calcium loss during total parenteral nutrition: effect of phosphorus. (published abstract); American Society for Bone and Mineral Research; 1985;
Wood RJ, Sitrin MD, Rosenberg IH; Calciuria in total parenteral nutrition: effects of amino acids and glucose in rats.; Am J Clin Nutr; 1984 Jul; 40(1); 101-106
Bengoa JM, Sitrin MD, Meredith S, Kelly SE, Shah N, Baker AL, Rosenberg IH; Intestinal calcium absorption and vitamin D status in chronic cholestatic liver disease.; Hepatology; 1984 Mar; 4(2); 261-265
Hanauer S.B., Sitrin MD, Bengoa JB, Newcomb S.A., Kirsner J.B.; Long term follow up of patients with Crohn's disease treated by supportive total parenteral nutrition. (published abstract); Gastroenterology; 1984; 86; 1106
Kushner R.F., Cusson G.J., Smith M.W., Walker J.G., Sitrin MD; Treatment of selected patients with active Crohn's disease by prolonged bowel rest and home parenteral nutrition (HPN. (published abstract); Gastroenterology; 1984; 86(5); 1148
Bengoa JM, Sitrin MD, Wood RJ, Rosenberg IH; Amino acid-induced hypercalciuria in patients on total parenteral nutrition.; Am J Clin Nutr; 1983 Aug; 38(2); 264-269
Bengoa J.M., Sitrin MD, Wood R.J., Rosenberg I.H.; Amino acid induced hypercalciuria during total parenteral nutrition (TPN). (published abstract); Clinical Research; 1983; 31; -614A
Wood R.J., Sitrin MD, Rosenberg I.H.; Amino acid induced hypercalciuria in rats receiving total parenteral nutrition (TPN). (published abstract); FASEB; 1983;
Singh K., Weinberg R., Sitrin MD, Rosenberg I.H.; Changes in serum lipid levels in patients receiving total parenteral nutrition. (published abstract); Clinical Research; 1983; 31; 623A
Bengoa J.M., Sitrin MD, Rosenberg I.H.; Comparison of vitamin D and 25 hydroxyvitamin D absorption in patients with chronic cholestatic liver disease. (published abstract); Gastroenterology; 1983; 84; 1102
Bolt M.J.G., Sitrin MD; Elevated fasting and postprandial unconjugated serum bile acids in small bowel bacterial overgrowth. (published abstract); Gastroenterology; 1983; 84; 111
Wood R.J., Bengoa J.M., Sitrin MD, Rosenberg I.H.; Increased urinary losses of calcium, phosphorus and magnesium in patients receiving cyclic versus continuous total parenteral nutrition. (published abstract); Clinical Research; 1983; 31; 246A
Lieberman F., Noronha A., Sitrin MD; Reversal of ophthalmoplegia in cystic fibrosis after prolonged high dose parenteral vitamin E therapy. (published abstract); ANN; 1983;
Sitrin MD, Jensen W.E., Lieberman F., Addington W.; Reversible neurologic disease caused by vitamin E deficiency in an adult with cystic fibrosis. (published abstract); Gastroenterology; 1983; 84; 1312
Klein F.S., Sitrin MD, Lawler M., Lin C.C.; The effect of total parenteral nutrition (TPN) on the outcome of pregnancy. (published abstract); American Dietetic Association; 1983;
Weinberg RB, Sitrin MD, Adkins GM, Lin CC; Treatment of hyperlipidemic pancreatitis in pregnancy with total parenteral nutrition.; Gastroenterology; 1982 Dec; 83(6); 1300-1305
Sitrin MD, Pollack KL, Bolt MJ, Rosenberg IH; Comparison of vitamin D and 25-hydroxyvitamin D absorption in the rat.; Am J Physiol; 1982 Apr; 242(4); 326-332
Sitrin MD, Schoeller D.A., van Santen E., et al.; Development of a protein absorption test using a stable isotope labeled protein. (published abstract); Gastroenterology; 1982; 82; 1182
Hanauer S.B., Bengoa J.M., Sitrin MD, Rosenberg I.H.; Influence of fistula, perianal disease and obstruction on response of patients with Crohn's disease (CD) to parenteral nutrition (PN) and bowel rest (BR). (published abstract); Gastroenterology; 1982; 82; 1078
Bengoa J.M., Hanauer M.D., Sitrin MD, et al.; Pattern and prognosis of hepatic dysfunction during parenteral nutrition (PN) in inflammatory bowel disease (IBD. (published abstract); Gastroenterology; 1982; 82; 1016
Bengoa J.M., Sitrin MD, Kelly S., et al.; Serum 25 hydroxyvitamin D, calcium absorption and bone histology in chronic cholestatic liver disease. (published abstract); Clinical Research; 1982; 30; 618A
Rosenberg IH, Sitrin MD; Screening for fat malabsorption.; Ann Intern Med; 1981 Dec; 95(6); 776-777
Bolt MJ, Sitrin MD, Favus MJ, Rosenberg IH; Hepatic vitamin D 25-hydroxylase: inhibition by bile duct ligation or bile salts.; Hepatology; 1981 Sep; 1(5); 436-440
Pollack K.L., Sitrin MD, Rosenberg I.H.; Chylomicron dependent absorption and transport of vitamin D (D) and 25 hydroxyvitamin D (25 OHD) in the rat. (published abstract); Clinical Research; 1981; 29; 268A
Sitrin MD, Pollack K.L., Rosenberg I.H.; Influence of bile salts and fat on intestinal absorption of vitamin D (D) and 25 hydroxyvitamin D (25 OHD) in the rat. (published abstract); Clinical Research; 1981; 29; 630A
Sitrin MD, Pollack K.L., Rosenberg I.H.; Intestinal absorption of 1,25 (OH)2 in the rat. (pubished abstract); Gastroenterology; 1981; 80; 1288
Sitrin MD, Rosenberg IH, Chawla K, Meredith S, Sellin J, Rabb JM, Coe F, Kirsner JB, Kraft SC; Nutritional and metabolic complications in a patient with Crohn's disease and ileal resection.; Gastroenterology; 1980 May; 78(5 Pt); 1069-1079
Kelly S., Sellin J.H,, Meredith S.C., Sitrin MD, et al.; Calcium absorption, vitamin D status and bone disease after bowel resection for Crohn's disease. (published abstract); Gastroenterology; 1980; 78; 1193
Sitrin MD, et al.; Comparison of vitamin D (D) and 25 OH vitamin D (25 OH D) absorption in the rat. (published abstract); Gastroenterology; 1980; 78; 1263
Sitrin MD, Bolt M.J.G., Rosenberg I.H.; Characterization and quantitative analysis of the biliary excretion products of vitamin D and 25-OH vitamin D (25-OH D). (published abstract); Clinical Research; 1978; 26; 285A
Sitrin MD, Bolt M.J.G., Rosenberg I.H.; Enterohepatic circulation of water soluble metabolites of 25 OH vitamin D. (published abstract); Gastroenterology; 1978; 74; 1146
Rabb J., Sellin J.H., Sitrin MD, et al.; Reduction of urinary calcium oxalate activity product ratio by dietary calcium in Crohn‘s disease. (published abstract); Gastroenterology; 1978; 76; 1221
Bolt MJ, Sitrin MD, Favus MJ, Rosenberg IH; Hepatic vitamin D 25-hydroxylase: inhibition by bile duct ligation or bile salts. (published abstract); Clinical Research; 1977; 25; 606A
Sitrin MD, Bohr DF; Ca and Na interaction in vascular smooth muscle contraction.; Am J Physiol; 1971 Apr; 220(4); 1124-1128
Bohr DF, Sitrin MD, Hansen TR; Vascular smooth muscle in experimental hypertension.; Clin Sci; 1971 Feb; 40(2); 1-1
SITRIN MD; Regulation of vascular smooth muscle contraction: Changes in experimental hypertension.; Supplement II to Circulation Research, Vols XXVI and XXVII, pp. 11 83 and 11 90, October 1970.; 1970;
Sitrin MD; Changes in serum lipid levels in patients receiving total parenteral nutrition. (published abstract); Clinical Research;
Barak N, Wall-Alonso E, Sitrin MD; Evaluation of stress factors and body weight adjustments currently used to estimate energy expenditure in hospitalized patients.; JPEN J Parenter Enteral Nutr; 26(4); 231-238
Bengoa JM, Sitrin MD, Meredith S, Kelly SE, Shah N, Baker AL, Rosenberg IH; Intestinal calcium absorption and vitamin D status in chronic cholestatic liver disease.; Hepatology; 4(2); 261-265
Bengoa JM, Hanauer SB, Sitrin MD, Baker AL, Rosenberg IH; Pattern and prognosis of liver function test abnormalities during parenteral nutrition in inflammatory bowel disease.; Hepatology; 5(1); 79-84
Yen, R., Pomakov O.A., Sitrin MD; Relationship of proximal hyperplastic polyps to adenomas on screening colonoscopy. (published abstract); Gastroenterology; 134; A486
Barak N, Wall-Alonso E, Cheng A, Sitrin MD; Use of bioelectrical impedance analysis to predict energy expenditure of hospitalized patients receiving nutrition support.; JPEN J Parenter Enteral Nutr; 27(1); 43-46


GRANTS

January 2007 to December 2008
A Multicenter, Randomized, Placebo-Controlled, Double-Blinded Study of the Efficacy and Safety of Lubiprostone in Patients with Opioid-Induced Bowel Dysfunction,
Sucampo/Takeda Pharmaceuticals
Michael Sitrin, Jeffrey Lackner
$30,000
January 2007 to December 2008
Procurement of fasting blood samples for use in the development of a gastrointestinal disease test panel.
Prometheus Laboratories
Michael Sitrin, Jeffrey Lackner
$12,750
January 2006 to December 2007
A randomized, double-blind, placebo-controlled, parallel-group, multicenter study to evaluate the efficacy and safety of DNK333 25 mg b.i.d. given orally for 4 weeks in female patients with Diarrhea-predominant Irritable Bowel Syndrome (IBS-D)
Novartis Pharmaceutical
Michael Sitrin, Jeffrey Lackner
$45,000
April 1997 to March 2004
Rat intestinal membranes: vitamin D mediated effects .
NIH
Michael Sitrin
$196,835

“Development of a mouse model of NASH”
VA VISN 2 Research Incentive Funds 2004
Michael Sitrin
$15,000