Dr. John Sullivan
Ophthalmology
VA Western NY Healthcare System
Medical Research, Bldg 20, Rm 245
3495 Bailey Ave
Buffalo NY, 14215
Phone: (716) 862-6533
Fax: (716) 862-6526
Email: js354@buffalo.edu

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OFFICE LOCATIONS

VA Medical Center
3495 Bailey Ave
Buffalo NY, 14215

Phone: 716-862-6533
View map


SPECIALTIES

Retina
Gene therapy
Neurodegenerative disorders
Pathophysiology
Protein folding and structure
Regulation of gene expression
Signal Transduction


EDUCATION

1994 Postdoctoral Fellow, Biophysics
University of Michigan, Ann Arbor, MI
1992 Postdoctoral Fellow, Biophysics
Washington Univ. School Medicine, St. Louis MO
1987 MD, PhD, Medicine/Biophysics
Mount Sinai School Medicine, NY
1979 Bachelor of Arts, Microbiology
Rutgers University, New Brunswick, NJ


PUBLICATIONS

Brueggemann LI, Sullivan JM; HEK293S cells have functional retinoid processing machinery.; J Gen Physiol; 2002 Jun; 119(6); 593-612
Sullivan JM, Pietras KM, Shin BJ, Misasi JN; Hammerhead ribozymes designed to cleave all human rod opsin mRNAs which cause autosomal dominant retinitis pigmentosa.; Mol Vis; 2002 Apr; 8; 102-113
SULLIVAN J Pietras K Shin BJ JN Misasi; Hammerhead ribozymes designed to cleave all human rod opsin mRNAs which cause autosomal dominant retinitis pigmentosa.; Molecular Vision; 2002; 8; 102-113
SULLIVAN J Brueggemann L; . all-trans-Retinal forms a visible-absorbing pigment with human rod opsin.; Biochemistry; 2001; 40; 4446-4453
SULLIVAN J; Rhodopsin charge motions in the Schiff base counterion mutant E113Q; Invest. Ophthal. Vis. Sci; 2001; 42(S184);
SULLIVAN J Brueggemann L Anumonwo J; Voltage and proton sensitivity of rhodopsin activation; Biophys. J.; 2001; 80(19a);
SULLIVAN J MF Satchwell; . . Development of stable cell lines expressing high levels of point mutants of human opsin for biochemical and biophysical studies. .; Methods in Enzymology; 2000; 315; 30-58
SULLIVAN J L Brueggemann P Shukla; An electrical approach to study rhodopsin activation in single cells with the early receptor current assay; Methods in Enzymology; 2000; 315; 268-293
SULLIVAN JM Brueggemann L; HEK293S cells have functional retinoid processing machinery; Invest. Ophthal. Vis. Sci; 2000; 41(S616);
SULLIVAN J L Chiu GM Seigel; Rhodopsin-induced apoptosis in a human cell culture system; Invest. Ophthal. Vis. Sci; 2000 Jan; 41(S404);
Shukla P, Sullivan JM; Normal and mutant rhodopsin activation measured with the early receptor current in a unicellular expression system.; J Gen Physiol; 1999 Nov; 114(5); 609-636
Sullivan JM, Shukla P; Time-resolved rhodopsin activation currents in a unicellular expression system.; Biophys J; 1999 Sep; 77(3); 1333-1357
SULLIVAN J Shukla P; Normal and mutant rhodopsin activation measured with the early receptor current in a unicellular expression system.; J. General Physiology; 1999; 114; 609-636
SULLIVAN JM L Brueggemann P Shukla; Rhodopsin senses the transmembrane electrostatic field; Invest. Ophthal. Vis. Sci.; 1999; 40(S211);
SULLIVAN J Shukla P ; Time-resolved rhodopsin activation currents in a unicellular expression system; Biophysical J; 1999; 77(3); 1333-1357
SULLIVAN J P Shukla; Time-resolved rhodopsin activation: early receptor current studies in a unicellular expression system.; Biophys. J; 1999; 76(148a);
SULLIVAN J; . Low-cost monochromatic microsecond flash microbeam apparatus for single-cell photolysis of rhodopsin or other photolabile pigments.; Rev. Sci. Inst; 1998;
SULLIVAN J Pietras KM Shin B; Design and testing of hammerhead ribozymes to cleave full-length opsin mRNA; Invest. Ophthal. Vis. Sci.; 1998; 39(S722);
SULLIVAN J Satchwell MF; Development of stable cell lines expressing mutant human rhodopsins; Invest. Ophthal. Vis. Sci; 1998; 39(S958);
SULLIVAN J Mason GO J Olik; A sutureless self-retaining infusion cannula for pars plana vitrectomy; Amer. J. Ophthalmol; 1990; 110; 577-578
SULLIVAN J Liebovitch LS; Fractal analysis of a voltage dependent potassium channel from cultured mouse hippocampal neurons; Biophysical J; 1987; 52; 979-988
SULLIVAN J Brueggemann L; HEK293S cells have functional retinoid processing machinery.; J. Gen. Physiol; 119; 593-612


GRANTS

September 2003 to September 2007
A Ribozyme Rescue Strategy for Autosomal Dominant Retinitis Pigmentosa
National Eye Institute
John Sullivan
$975,000
June 1996 to May 2001
The Early Receptor Current of Rhodopsin Activation
National Eye Institute
John Sullivan
$350,000



 
Dr. John Sullivan
Dr. John Sullivan