Dr. Anders Hakansson Microbiology and Immunology 145 Biomedical Research Building Buffalo NY, 14214 Phone: (716) 829-2907 Email: andersh@buffalo.edu View map

EDUCATION

1999	Ph.D., Medical Microbiology Lund University
1997	Bachelor of Medicine, Lund University Medical School

PUBLICATIONS

Daniels, C.C., Briles, T.C., Mirza, S., Hakansson AP, Briles, D.E.; Capsule does not block antibody binding to PspA, a surface virulence protein of streptococcus pneumoniae; Microbial Path.; 2006; 40; 228-223

Michos, A., Gryllos, I., Hakansson AP, Srivastava, A., Kokkotou, A., Wessels, M.R.; Enhancement of streptolysin O activity and intrinsic cytotoxic effects of the group A streptococcal toxin, NAD-glycohydrolase; J. Biol. Chem.; 2006; 281; 8216-8223

Hakansson AP, Cywes Bentley, C., Shakhnovic, E.A., Wessels, M.R.; Cytolysin-dependent evasion of lysosomal killing; Proc. Natl. Acad. Sci. USA; 2005; 102; 5192-5197

Hakansson AP; Extracellular group A Streptococcus induces keratinocyte apoptosisby dysregulating calcium signaling; Cell Microbiol.; 2005; 7; 945-955

Roche, H., Hakansson AP, Hollingshead, S.K., Briles, D. E.; Regions of PspA/EF3296 best able to elicit protection against Streptococcus pneumoniae in a murine infection model; Infect. Immun.; 2003; 71; 1033-1041

Roche, H., Ren, B., MacDaniel, L., Hakansson AP, Briles, D.E.; Relative roles of genetic background and variation of PspA in the ability of antibodies to PspA to protect against capsular type 3 and 4 strains of Streptococcus pneumoniae; Infect. Immun.; 2003; 71; 4498-4505

Smith, AW, Roche, H., Trombe, MC, Briles, DE, Hakansson AP; Characterization of the dihydrolipoamide dehydrogenase from Streptococcus pneumoniae and its role in virulence; Mol. Microbiol.; 2002; 44; 431-448

Hakansson AP, Roche, H., Mizra, S., McDaniel, L., Brooks-Walter, A., Briles, DE; Characterization of the binding of human lactoferrin to pneumococcal surface protein A.; Infect. Immun.; 2001; 69; 3372-3381

Yrlid, U., Svensson, M., Hakansson AP, Chambers, B.J., Ljunggren, H-G, Wick, MJ; In vivo activationof dendritic cells and T cells during Salmonella typhimurium; Infect. Immun.; 2001; 69; 5726-5735

Mizusawa, H., Hedlund, P., Hakansson AP, Alm, P., Andersson, K-E.; Morphological and functional in vitro and in vivo characterizationof the mouse corpus cavernosum; Br. J. Pharmacol.; 2001; 132; 1333-1341

Hakansson AP, Svensson, M., Mossberg, A-K, Sabharwal,l H., Linse, S., Lazou, I., Lonnerdal, B., Svanborg, C.; A folding variant of alpha-lactalbumin with bactericidal activity against Streptococcus pneumoniae; Mol. Microbiol.; 2000; 35; 589-600

Kohler, C., Gogvadze, V., Hakansson AP, Svanborg, C., Orrenius, S., Zhivotovsky, B.; A folding variant of human alpha-lactalbumin induces mitochondrial permeability transition in isolated mitochondria; Eur. J. Biochem.; 2000; 268; 186-191

Svensson, M., Hakansson AP, Mossberg, A-K, Linse, S., Svanborg, C.; Conversion of alpha-lactalbumin to a protein inducing apoptosis; Proc. Natl. Acad. Sci. USA; 2000; 97; 4221-4226

Hakansson AP, Andreasson, J., Zhivotovsky, B., Karpman, D., Orrenius, S., Svanborg, C.; Multimeric alpha-lactalbumin from human milk induces apoptosis through a direct effect on cell nuclei; Exp. Cell Res.; 1999; 246; 451-460

Kohler, C., Hakansson AP, Svanborg, S., Orrenius, S., Zhivotovsky, B.; Protease activation in multimeric alpha-lactalbumin induced apoptosis; Exp. Cell Res.; 1999; 249; 260-268

Svensson, M., Sabharwal, H., Hakansson AP, Mossberg, A-K, Lipniunas, P., Leffler, H., Svanborg, C., Linse, S.; Spectroscopic characteriation of alpha-lactalbumin folding variants that induce apoptosis in tumor cells; J. Biol. Chem.; 1999; 274; 6388-6396

Karpman, D., Hakansson AP, Perez, M-T, Isaksson, C., Caprioli, A., Svanborg, C.; Apoptosis of renal cortical cells in hemolytic uremic syndrome: in vivo and in vitro studies; Infect. Immun.; 1998; 66; 636-644

Perez, MT, Arner, K., Hakansson AP; DNA fragmentation characteristic of apoptosis and cell loss induced by kainic acid in rabbit retina; Neurochem. Internat.; 1997; 31; 251-260

von Andersson, Rosen I, Hakansson AP, Aniansson, G., Hansson, C., Andersson, B., Sabharwall, H., Svanborg, C.; Antibodies to pneumococcal polysaccharides in human milk: relationship to colonization and acute otitis media; Pediatr. Infect. Dis. J.; 1996; 15; 498-507

Hakansson AP, Zhivotovsky, B., Orrenius, S., Sabharwal, H., Svanborg, C.; Apoptosis induced by a human milk protein; Proc. Natl. Acad. Sci.; 1995; 92; 8064-8068

Davies, J., Carlstedt, I., Nilsson, A-K, Hakansson AP, Sabharwal, H., Svanborg, C.; Binding of Haemophilus influenzae to purified mucins from the human respiratory tract; Infect. Immun.; 1995; 63; 2485-2492

Aniansson, G., Alm, B., Andersson, B., Hakansson AP, Larsson, P., Nylen, O., Peterson, H., Rigner, P., Svanborg, M., Sabharwal, H., Svanborg, C.; A prospective, cohort study on breast feeding and otitis media in Swedish infants.; Pediatr. Infec. Dis. J.; 1994; 13; 183-188

Hakansson AP, Kidd, A., Wadell, G., Sabharwal, H., Svanborg, C.; Adenovirus infection enhances the invitro adherence of Streptococcus pneumoniae; Infect. Immun.; 1994; 62; 2707-2714

GRANTS

January 2002 Bacterial respiratory pathogen research unit contract interaction of Group A Streptococcus with pharyngeal epithelial cells NIH Anders Hakansson

Apoptosis induced by a human milk protein complex Swedish Cancer Society Anders Hakansson