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DESCRIPTION OF INTERESTS
| I am a developmental biologist studying the genetic and molecular mechanisms underlying the formation of vertebrate retina during embryogenesis. |
EDUCATION
| 1994 |
Doctor of Philosophy, Biochemistry and Molecular Biology
Peking Union Medical College
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| 1989 |
Doctor of Medicine, Medicine
Qingdao Medical College
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PUBLICATIONS
| Fu X, Kiyama T, Li R, Russell M, Klein WH, Mu X; Epitope-tagging Math5 and Pou4f2: new tools to study retinal ganglion cell development in the mouse.; Dev Dyn; 2009 Sep; 238(9); 2309-2317 |
| Cho JH, Mu X, Wang SW, Klein WH; Retinal ganglion cell death and optic nerve degeneration by genetic ablation in adult mice.; Exp Eye Res; 2009 Mar; 88(3); 542-552 |
| Sapieha P, Sirinyan M, Hamel D, Zaniolo K, Joyal JS, Cho JH, Honoré JC, Kermorvant-Duchemin E, Varma DR, Tremblay S, Leduc M, Rihakova L, Hardy P, Klein WH, Mu X, Mamer O, Lachapelle P, Di Polo A, Beauséjour C, Andelfinger G, Mitchell G, Sennlaub F, Chemtob S; The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis.; Nat Med; 2008 Oct; 14(10); 1067-1076 |
| Mu X, Fu X, Beremand PD, Thomas TL, Klein WH; Gene regulation logic in retinal ganglion cell development: Isl1 defines a critical branch distinct from but overlapping with Pou4f2.; Proc Natl Acad Sci U S A; 2008 May; 105(19); 6942-6947 |
| Burke RD, Angerer LM, Elphick MR, Humphrey GW, Yaguchi S, Kiyama T, Liang S, Mu X, Agca C, Klein WH, Brandhorst BP, Rowe M, Wilson K, Churcher AM, Taylor JS, Chen N, Murray G, Wang D, Mellott D, Olinski R, Hallböök F, Thorndyke MC; A genomic view of the sea urchin nervous system.; Dev Biol; 2006 Dec; 300(1); 434-460 |
| Fu X, Sun H, Klein WH, Mu X; Beta-catenin is essential for lamination but not neurogenesis in mouse retinal development.; Dev Biol; 2006 Nov; 299(2); 424-437 |
| Sodergren E, Weinstock GM, Davidson EH, Cameron RA, Gibbs RA, Angerer RC, Angerer LM, Arnone MI, Burgess DR, Burke RD, Coffman JA, Dean M, Elphick MR, Ettensohn CA, Foltz KR, Hamdoun A, Hynes RO, Klein WH, Marzluff W, McClay DR, Morris RL, Mushegian A, Rast JP, Smith LC, Thorndyke MC, Vacquier VD, Wessel GM, Wray G, Zhang L, Elsik CG, Ermolaeva O, Hlavina W, Hofmann G, Kitts P, Landrum MJ, Mackey AJ, Maglott D, Panopoulou G, Poustka AJ, Pruitt K, Sapojnikov V, Song X, Souvorov A, Solovyev V, Wei Z, Whittaker CA, Worley K, Durbin KJ, Shen Y, Fedrigo O, Garfield D, Haygood R, Primus A, Satija R, Severson T, Gonzalez-Garay ML, Jackson AR, Milosavljevic A, Tong M, Killian CE, Livingston BT, Wilt FH, Adams N, Bellé R, Carbonneau S, Cheung R, Cormier P, Cosson B, Croce J, Fernandez-Guerra A, Genevičre AM, Goel M, Kelkar H, Morales J, Mulner-Lorillon O, Robertson AJ, Goldstone JV, Cole B, Epel D, Gold B, Hahn ME, Howard-Ashby M, Scally M, Stegeman JJ, Allgood EL, Cool J, Judkins KM, McCafferty SS, Musante AM, Obar RA, Rawson AP, Rossetti BJ, Gibbons IR, Hoffman MP, Leone A, Istrail S, Materna SC, Samanta MP, Stolc V, Tongprasit W, Tu Q, Bergeron KF, Brandhorst BP, Whittle J, Berney K, Bottjer DJ, Calestani C, Peterson K, Chow E, Yuan QA, Elhaik E, Graur D, Reese JT, Bosdet I, Heesun S, Marra MA, Schein J, Anderson MK, Brockton V, Buckley KM, Cohen AH, Fugmann SD, Hibino T, Loza-Coll M, Majeske AJ, Messier C, Nair SV, Pancer Z, Terwilliger DP, Agca C, Arboleda E, Chen N, Churcher AM, Hallböök F, Humphrey GW, Idris MM, Kiyama T, Liang S, Mellott D, Mu X, Murray G, Olinski RP, Raible F, Rowe M, Taylor JS, Tessmar-Raible K, Wang D, Wilson KH, Yaguchi S, Gaasterland T, Galindo BE, Gunaratne HJ, Juliano C, Kinukawa M, Moy GW, Neill AT, Nomura M, Raisch M, Reade A, Roux MM, Song JL, Su YH, Townley IK, Voronina E, Wong JL, Amore G, Branno M, Brown ER, Cavalieri V, Duboc V, Duloquin L, Flytzanis C, Gache C, Lapraz F, Lepage T, Locascio A, Martinez P, Matassi G, Matranga V, Range R, Rizzo F, Röttinger E, Beane W, Bradham C, Byrum C, Glenn T, Hussain S, Manning G, Miranda E, Thomason R, Walton K, Wikramanayke A, Wu SY, Xu R, Brown CT, Chen L, Gray RF, Lee PY, Nam J, Oliveri P, Smith J, Muzny D, Bell S, Chacko J, Cree A, Curry S, Davis C, Dinh H, Dugan-Rocha S, Fowler J, Gill R, Hamilton C, Hernandez J, Hines S, Hume J, Jackson L, Jolivet A, Kovar C, Lee S, Lewis L, Miner G, Morgan M, Nazareth LV, Okwuonu G, Parker D, Pu LL, Thorn R, Wright R; The genome of the sea urchin Strongylocentrotus purpuratus.; Science; 2006 Nov; 314(5801); 941-952 |
| Mu X, Fu X, Sun H, Beremand PD, Thomas TL, Klein WH; A gene network downstream of transcription factor Math5 regulates retinal progenitor cell competence and ganglion cell fate.; Dev Biol; 2005 Apr; 280(2); 467-481 |
| Mu X, Fu X, Sun H, Liang S, Maeda H, Frishman LJ, Klein WH; Ganglion cells are required for normal progenitor- cell proliferation but not cell-fate determination or patterning in the developing mouse retina.; Curr Biol; 2005 Mar; 15(6); 525-530 |
| Liang S, Zhao S, Mu X, Thomas T, Klein WH; Novel retinal genes discovered by mining the mouse embryonic RetinalExpress database.; Mol Vis; 2004 Oct; 10; 773-786 |
| Mu X, Beremand PD, Zhao S, Pershad R, Sun H, Scarpa A, Liang S, Thomas TL, Klein WH; Discrete gene sets depend on POU domain transcription factor Brn3b/Brn-3.2/POU4f2 for their expression in the mouse embryonic retina.; Development; 2004 Mar; 131(6); 1197-1210 |
| Mu X, Klein WH; A gene regulatory hierarchy for retinal ganglion cell specification and differentiation.; Semin Cell Dev Biol; 2004 Feb; 15(1); 115-123 |
| Fortunel NO, Otu HH, Ng HH, Chen J, Mu X, Chevassut T, Li X, Joseph M, Bailey C, Hatzfeld JA, Hatzfeld A, Usta F, Vega VB, Long PM, Libermann TA, Lim B; Comment on " 'Stemness': transcriptional profiling of embryonic and adult stem cells" and "a stem cell molecular signature".; Science; 2003 Oct; 302(5644); 393-393 |
| Wang SW, Mu X, Bowers WJ, Klein WH; Retinal ganglion cell differentiation in cultured mouse retinal explants.; Methods; 2002 Dec; 28(4); 448-456 |
| Wang SW, Mu X, Bowers WJ, Kim DS, Plas DJ, Crair MC, Federoff HJ, Gan L, Klein WH; Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon outgrowth.; Development; 2002 Jan; 129(2); 467-477 |
| Mu X, Zhao S, Pershad R, Hsieh TF, Scarpa A, Wang SW, White RA, Beremand PD, Thomas TL, Gan L, Klein WH; Gene expression in the developing mouse retina by EST sequencing and microarray analysis.; Nucleic Acids Res; 2001 Dec; 29(24); 4983-4993 |
| Mu X, Spanos SA, Shiloach J, Kimmel A; CRTF is a novel transcription factor that regulates multiple stages of Dictyostelium development.; Development; 2001 Jul; 128(13); 2569-2579 |
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