Dr. Margarita Dubocovich
Pharmacology And Toxicology
Professor and Chair
102 Farber Hall
Buffalo NY, 14214
Phone: (716) 829-3048
Email: mdubo@buffalo.edu

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OFFICE LOCATIONS

Dubocovich Labs
130 Farber Hall
122 Farber Hall
108 Farber Hall


Phone: 829-2811
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PUBLICATIONS

Dubocovich ML, Dubocovich M; Melatonin receptors: role on sleep and circadian rhythm regulation.; Sleep Med; 2007 Dec; 8 Sup; 34-42
Masana MI, Sumaya IC, Becker-Andre M, Dubocovich ML, Dubocovich M; Behavioral characterization and modulation of circadian rhythms by light and melatonin in C3H/HeN mice homozygous for the RORbeta knockout.; Am J Physiol Regul Integr Comp Physiol; 2007 Jun; 292(6); 2357-2367
Dubocovich ML; Agomelatine targets a range of major depressive disorder symptoms.; Curr Opin Investig Drugs; 2006 Jul; 7(7); 670-680
Blask DE, Brainard GC, Dauchy RT, Hanifin JP, Davidson LK, Krause JA, Sauer LA, Rivera-Bermudez MA, Dubocovich ML, Jasser SA, Lynch DT, Rollag MD, Zalatan F; Melatonin-depleted blood from premenopausal women exposed to light at night stimulates growth of human breast cancer xenografts in nude rats.; Cancer Res; 2005 Dec; 65(23); 11174-11184
Mundey K, Benloucif S, Harsanyi K, Dubocovich ML, Zee PC; Phase-dependent treatment of delayed sleep phase syndrome with melatonin.; Sleep; 2005 Oct; 28(10); 1271-1278
Dubocovich ML, Hudson RL, Sumaya IC, Masana MI, Manna E; Effect of MT1 melatonin receptor deletion on melatonin-mediated phase shift of circadian rhythms in the C57BL/6 mouse.; J Pineal Res; 2005 Sep; 39(2); 113-120
Sumaya IC, Masana MI, Dubocovich ML; The antidepressant-like effect of the melatonin receptor ligand luzindole in mice during forced swimming requires expression of MT2 but not MT1 melatonin receptors.; J Pineal Res; 2005 Sep; 39(2); 170-177
Dubocovich ML, Markowska M; Functional MT1 and MT2 melatonin receptors in mammals.; Endocrine; 2005 Jul; 27(2); 101-110
Hansen M, Janssen I, Schiff A, Zee PC, Dubocovich ML; The impact of school daily schedule on adolescent sleep.; Pediatrics; 2005 Jun; 115(6); 1555-1561
Masana MI, Soares JM, Dubocovich ML; 17Beta-estradiol modulates hMT1 melatonin receptor function.; Neuroendocrinology; 2005 Apr; 81(2); 87-95
Gerdin MJ, Masana MI, Rivera-Bermúdez MA, Hudson RL, Earnest DJ, Gillette MU, Dubocovich ML; Melatonin desensitizes endogenous MT2 melatonin receptors in the rat suprachiasmatic nucleus: relevance for defining the periods of sensitivity of the mammalian circadian clock to melatonin.; FASEB J; 2004 Nov; 18(14); 1646-1656
Gerdin MJ, Dubocovich ML; Key MT2 melatonin receptor citation still buried - dig deeper!; J Pineal Res; 2004 Sep; 37(2); 142-142
Gerdin MJ, Masana MI, Dubocovich ML; Melatonin-mediated regulation of human MT(1) melatonin receptors expressed in mammalian cells.; Biochem Pharmacol; 2004 Jun; 67(11); 2023-2030
Rivera-Bermúdez MA, Masana MI, Brown GM, Earnest DJ, Dubocovich ML; Immortalized cells from the rat suprachiasmatic nucleus express functional melatonin receptors.; Brain Res; 2004 Mar; 1002(1-2); 21-27
Dubocovich ML, Rivera-Bermudez MA, Gerdin MJ, Masana MI; Molecular pharmacology, regulation and function of mammalian melatonin receptors.; Front Biosci; 2003 Sep; 8; 1093-1108
Soares JM, Masana MI, Ersahin C, Dubocovich ML; Functional melatonin receptors in rat ovaries at various stages of the estrous cycle.; J Pharmacol Exp Ther; 2003 Aug; 306(2); 694-702
Gerdin MJ, Mseeh F, Dubocovich ML; Mutagenesis studies of the human MT2 melatonin receptor.; Biochem Pharmacol; 2003 Jul; 66(2); 315-320
Rivera-Bermúdez MA, Gerdin MJ, Earnest DJ, Dubocovich ML; Regulation of basal rhythmicity in protein kinase C activity by melatonin in immortalized rat suprachiasmatic nucleus cells.; Neurosci Lett; 2003 Jul; 346(1-2); 37-40
Masana MI, Witt-Enderby PA, Dubocovich ML; Melatonin differentially modulates the expression and function of the hMT1 and hMT2 melatonin receptors upon prolonged withdrawal.; Biochem Pharmacol; 2003 Mar; 65(5); 731-739
Benloucif S, Masana MI, Zee PC, Dubocovich ML; Nimodipine potentiates light-induced phase shifts of circadian activity rhythms but not c-fos expression in the suprachiasmatic nucleus of mice.; Brain Res; 2003 Mar; 966(1); 157-161
Gerdin MJ, Masana MI, Ren D, Miller RJ, Dubocovich ML; Short-term exposure to melatonin differentially affects the functional sensitivity and trafficking of the hMT1 and hMT2 melatonin receptors.; J Pharmacol Exp Ther; 2003 Mar; 304(3); 931-939
Masana MI, Doolen S, Ersahin C, Al-Ghoul WM, Duckles SP, Dubocovich ML, Krause DN; MT(2) melatonin receptors are present and functional in rat caudal artery.; J Pharmacol Exp Ther; 2002 Sep; 302(3); 1295-1302
Yuan L, Collins AR, Dai J, Dubocovich ML, Hill SM; MT(1) melatonin receptor overexpression enhances the growth suppressive effect of melatonin in human breast cancer cells.; Mol Cell Endocrinol; 2002 Jun; 192(1-2); 147-156
Ersahin C, Masana MI, Dubocovich ML; Constitutively active melatonin MT(1) receptors in male rat caudal arteries.; Eur J Pharmacol; 2002 Mar; 439(1-3); 171-172
Lotufo CM, Lopes C, Dubocovich ML, Farsky SH, Markus RP; Melatonin and N-acetylserotonin inhibit leukocyte rolling and adhesion to rat microcirculation.; Eur J Pharmacol; 2001 Nov; 430(2-3); 351-357
Masana MI, Dubocovich ML; Melatonin receptor signaling: finding the path through the dark.; Sci STKE; 2001 Nov; 2001(107); 39-39
Reid KJ, Chang AM, Dubocovich ML, Turek FW, Takahashi JS, Zee PC; Familial advanced sleep phase syndrome.; Arch Neurol; 2001 Jul; 58(7); 1089-1094
Hunt AE, Al-Ghoul WM, Gillette MU, Dubocovich ML; Activation of MT(2) melatonin receptors in rat suprachiasmatic nucleus phase advances the circadian clock.; Am J Physiol Cell Physiol; 2001 Jan; 280(1); 110-118
Masana MI, Benloucif S, Dubocovich ML; Circadian rhythm of mt1 melatonin receptor expression in the suprachiasmatic nucleus of the C3H/HeN mouse.; J Pineal Res; 2000 Apr; 28(3); 185-192
Ruby NF, Dubocovich ML, Heller HC; Siberian hamsters that fail to reentrain to the photocycle have suppressed melatonin levels.; Am J Physiol Regul Integr Comp Physiol; 2000 Mar; 278(3); 757-762
Benloucif S, Bauer GL, Dubocovich ML, Finkel SI, Zee PC; Nimodipine potentiates the light-induced suppression of melatonin.; Neurosci Lett; 1999 Sep; 272(1); 67-71
Benloucif S, Masana MI, Yun K, Dubocovich ML; Interactions between light and melatonin on the circadian clock of mice.; J Biol Rhythms; 1999 Aug; 14(4); 281-289
Dubocovich ML, Masana MI, Benloucif S; Molecular pharmacology and function of melatonin receptor subtypes.; Adv Exp Med Biol; 1999 Jan; 460; 181-190



 
Dr. Margarita Dubocovich
Dr. Margarita Dubocovich